FGF12 and ZNF460

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FGF12	ZNF460
Description		fibroblast growth factor 12	zinc finger protein 460
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Space Nucleus Synapse	Nucleus
	Molecular Function	Protein Binding Growth Factor Activity Sodium Channel Regulator Activity Ion Channel Binding	DNA Binding Protein Binding Metal Ion Binding
	Biological Process	Regulation Of Membrane Depolarization Signal Transduction Cell-cell Signaling Chemical Synaptic Transmission Nervous System Development Heart Development Adult Locomotory Behavior Fibroblast Growth Factor Receptor Signaling Pathway Positive Regulation Of Sodium Ion Transport Neuromuscular Process Cardiac Muscle Cell Action Potential Involved In Contraction Regulation Of Neuronal Action Potential Regulation Of Sodium Ion Transmembrane Transport Regulation Of Voltage-gated Sodium Channel Activity Regulation Of Sodium Ion Transmembrane Transporter Activity Negative Regulation Of Cation Channel Activity	Regulation Of Transcription, DNA-templated
Pathways		Phase 0 - rapid depolarisation	Generic Transcription Pathway
Drugs
Diseases
GWAS		Age-related cognitive decline (memory) (slope of z-scores) ( 30954325) Bipolar disorder ( 31043756) Hip circumference adjusted for BMI ( 28552196) Idiopathic dilated cardiomyopathy ( 29495422) Ileal carcinoids ( 21139019) Major depressive disorder ( 23377640) Metabolite levels ( 19043545) Post bronchodilator FEV1/FVC ratio ( 26634245) Serum metabolite concentrations in chronic kidney disease ( 29545352) Severe influenza A (H1N1) infection ( 26379185) Sleep quality ( 23728906)	Heel bone mineral density ( 30598549)
Interacting Genes		18 interacting genes: AP2M1 APP COIL DACH1 DCTD DPPA2 IKZF1 LZTS2 MAPK13 MAPK8IP2 NEDD4 NEDD4L PJA1 SMURF1 SRPK1 SRPK2 YWHAE ZNF460	4 interacting genes: DEUP1 FGF12 MTNR1A ZNF250
Entrez ID		2257	10794
HPRD ID		03303	06885
Ensembl ID		ENSG00000114279	ENSG00000197714
Uniprot IDs		P61328	Q14592
PDB IDs		1Q1U 4JQ0
Enriched GO Terms of Interacting Partners?
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