THOC1 and FRA10AC1

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (two hybrid)

		THOC1	FRA10AC1
Description		THO complex 1	FRA10A associated CGG repeat 1
Image			No pdb structure
GO Annotations	Cellular Component	Transcription Export Complex THO Complex THO Complex Part Of Transcription Export Complex Nuclear Chromosome, Telomeric Region Nucleus Nucleoplasm Cytoplasm Nuclear Matrix Nuclear Speck	Nucleus
	Molecular Function	DNA Binding RNA Binding Protein Binding	Protein Binding
	Biological Process	Regulation Of DNA Recombination RNA Processing RNA Export From Nucleus MRNA Export From Nucleus Apoptotic Process Signal Transduction RNA Splicing MRNA 3'-end Processing Replication Fork Processing Regulation Of DNA-templated Transcription, Elongation Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus Negative Regulation Of Isotype Switching To IgA Isotypes Negative Regulation Of DNA Damage Checkpoint
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA 3'-end processing RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS		Bipolar disorder ( 20351715) Bipolar disorder or major depressive disorder ( 20351715) Height ( 31562340) Menarche (age at onset) ( 29773799)	Cerebrospinal AB1-42 levels in mild cognitive impairment ( 29274321) Cerebrospinal fluid AB1-42 levels ( 26252872 29274321)
Interacting Genes		14 interacting genes: ATP1B1 DHX8 FRA10AC1 IK MOAP1 MTNR1B NEDD4 RABGEF1 RB1 SAP30BP SF3B2 TRIM54 USHBP1 WDR77	27 interacting genes: ADPRS C7orf25 CHERP CWC27 EEF1D ESS2 GATD3A GDPD2 GLRX3 HABP4 IK KASH5 MAP3K12 MFAP1 NKAP PLPPR4 PRPF3 PRPF40A SAP30BP SF3B2 THOC1 TRIM41 TTC14 U2AF1 VPS29 ZCCHC10 ZNF830
Entrez ID		9984	118924
HPRD ID		09498	12319
Ensembl ID		ENSG00000079134	ENSG00000148690
Uniprot IDs		Q96FV9	Q70Z53
PDB IDs		1WXP
Enriched GO Terms of Interacting Partners?
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