RBM8A and UPF3B

Number of citations of the paper that reports this interaction (PubMedID 12718880)
111

Data Source:
BioGRID (pull down)
HPRD (in vivo)

		RBM8A	UPF3B
Description		RNA binding motif protein 8A	UPF3B regulator of nonsense mediated mRNA decay
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Cytosol Nuclear Speck Dendrite Exon-exon Junction Complex Neuronal Cell Body U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Centriolar Satellite Exon-exon Junction Complex
	Molecular Function	RNA Binding MRNA Binding Protein Binding	RNA Binding MRNA Binding Protein Binding Structural Constituent Of Nuclear Pore
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus Regulation Of Translation MRNA 3'-end Processing	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RNA Export From Nucleus MRNA Export From Nucleus MRNA 3'-end Processing Positive Regulation Of Translation
Pathways		Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)	Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases			Syndromic X-linked mental retardation, including: Turner type (MRXST); Siderius type (MRXSSD) ; Cabezas type (MRXC); Raymond type (MRXSR); Type10 (MRXS10); Type14 (MRXS14); Mental retardation with isolated growth hormone deficiency (MRGH)
GWAS
Interacting Genes		19 interacting genes: APP DPH1 EIF4A3 FBXO25 IKBKG IPO13 KAT2B MAGOH MAGOHB MCM7 NXF1 PDE4DIP RNPS1 SF3B2 SRPK1 SRPK2 TOE1 UPF3A UPF3B	13 interacting genes: EIF4A3 EIF6 EXOSC4 HBB MAGOH MCRS1 RBBP6 RBM8A SRPK2 TTC19 UPF1 UPF2 XRN1
Entrez ID		9939	65109
HPRD ID		05609	02247
Ensembl ID		ENSG00000265241	ENSG00000125351
Uniprot IDs		A0A023T787 Q9Y5S9	Q9BZI7
PDB IDs		1P27 2HYI 2J0Q 2J0S 2XB2 3EX7 5XJC 5YZG 6ICZ 6QDV	1UW4 2XB2
Enriched GO Terms of Interacting Partners?
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