EIF4A3 and CCDC174

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		EIF4A3	CCDC174
Description		eukaryotic translation initiation factor 4A3	coiled-coil domain containing 174
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Nucleolus Cytoplasm Cytosol Membrane Nuclear Speck Dendrite Exon-exon Junction Complex Neuronal Cell Body U2-type Catalytic Step 1 Spliceosome Catalytic Step 2 Spliceosome Glutamatergic Synapse Postsynaptic Cytosol	Nucleus Nucleoplasm
	Molecular Function	RNA Binding RNA Helicase Activity MRNA Binding Protein Binding ATP Binding Poly(A) Binding Selenocysteine Insertion Sequence Binding RNA Stem-loop Binding Ribonucleoprotein Complex Binding Translation Regulator Activity	Protein Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay MRNA Splicing, Via Spliceosome RRNA Processing RNA Export From Nucleus MRNA Export From Nucleus Associative Learning Response To Organic Cyclic Compound Negative Regulation Of Translation MRNA 3'-end Processing Exploration Behavior Positive Regulation Of Translation Embryonic Cranial Skeleton Morphogenesis Cellular Response To Selenite Ion Negative Regulation Of Excitatory Postsynaptic Potential Regulation Of Translation At Postsynapse, Modulating Synaptic Transmission Negative Regulation Of Selenocysteine Incorporation Negative Regulation Of Selenocysteine Insertion Sequence Binding Cellular Response To Brain-derived Neurotrophic Factor Stimulus
Pathways		ISG15 antiviral mechanism Transport of Mature mRNA derived from an Intron-Containing Transcript Deadenylation of mRNA mRNA Splicing - Major Pathway mRNA 3'-end processing RNA Polymerase II Transcription Termination Regulation of expression of SLITs and ROBOs Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)
Drugs
Diseases
GWAS		High light scatter reticulocyte count ( 27863252) High light scatter reticulocyte percentage of red cells ( 27863252) Immature fraction of reticulocytes ( 27863252) Myocardial infarction ( 26708285) Reticulocyte count ( 27863252) Reticulocyte fraction of red cells ( 27863252)	SjÃ¶gren's syndrome ( 28076899)
Interacting Genes		12 interacting genes: CASC3 CCDC174 CDCA7L CWC22 ESR1 MAGOH NXF1 PDCD4 RBM8A UPF1 UPF3B YWHAQ	1 interacting genes: EIF4A3
Entrez ID		9775	51244
HPRD ID		06482	12820
Ensembl ID		ENSG00000141543	ENSG00000154781
Uniprot IDs		A0A024R8W0 I3L3H2 P38919	A0A0B4J1R8 Q6PII3
PDB IDs		2HXY 2HYI 2J0Q 2J0S 2J0U 2XB2 3EX7 4C9B 5MQF 5XJC 5YZG 6ICZ 6QDV
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?