ZFYVE16 and TOM1

Number of citations of the paper that reports this interaction (PubMedID 14613930)
10

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid, in vitro, in vivo)

		ZFYVE16	TOM1
Description		zinc finger FYVE-type containing 16	target of myb1 membrane trafficking protein
Image
GO Annotations	Cellular Component	Early Endosome Cytosol Early Endosome Membrane Intracellular Membrane-bounded Organelle	Cytoplasm Endosome Early Endosome Cytosol Plasma Membrane Membrane Azurophil Granule Membrane Specific Granule Membrane Extracellular Exosome
	Molecular Function	Protein Binding 1-phosphatidylinositol Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Metal Ion Binding	Protein Binding Clathrin Binding
	Biological Process	Protein Targeting To Lysosome Signal Transduction Vesicle Organization Endosomal Transport Regulation Of Endocytosis BMP Signaling Pathway	Intracellular Protein Transport Endocytosis Protein Transport Endosomal Transport Neutrophil Degranulation
Pathways		Signaling by BMP	Neutrophil degranulation
Drugs
Diseases
GWAS		Blond vs. brown/black hair color ( 30531825) Psoriasis ( 25854761)	Cholesterol, total ( 24097068) HDL cholesterol ( 29404214) High density lipoprotein cholesterol levels ( 31217584) Hippocampal volume in mild cognitive impairment ( 29274321) Inflammatory bowel disease ( 28067908) Multiple myeloma ( 26007630) Multiple myeloma and monoclonal gammopathy ( 26007630) Plasma proprotein convertase subtilisin/kexin type 9 levels in stable coronary artery disease ( 29748315) Total cholesterol levels ( 28334899) Ulcerative colitis ( 28067908) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		5 interacting genes: APP EEA1 PPP1CA RNF11 TOM1	16 interacting genes: APP CLTC EEA1 ILVBL MAP3K1 MYO6 NEDD4 PTBP2 RPS27 SMURF1 SSBP2 TOLLIP UBC UBE2D1 ZFYVE16 ZNF512B
Entrez ID		9765	10043
HPRD ID		10319	05265
Ensembl ID		ENSG00000039319	ENSG00000100284
Uniprot IDs		Q7Z3T8	B3KUF5 O60784
PDB IDs		3T7L 5MK0	1ELK 1WRD 2N2N 2N9D 6J56
Enriched GO Terms of Interacting Partners?
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