CD79A and FCAR

Number of citations of the paper that reports this interaction (PubMedID 10438530)
30

Data Source:
HPRD (in vivo)

		CD79A	FCAR
Description		CD79a molecule	Fc fragment of IgA receptor
Image
GO Annotations	Cellular Component	Multivesicular Body Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane B Cell Receptor Complex Membrane Raft	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding	IgA Binding
	Biological Process	Adaptive Immune Response B Cell Differentiation B Cell Proliferation B Cell Activation B Cell Receptor Signaling Pathway	Immune Response Neutrophil Degranulation
Pathways		CD22 mediated BCR regulation Antigen activates B Cell Receptor (BCR) leading to generation of second messengers Antigen activates B Cell Receptor (BCR) leading to generation of second messengers	Neutrophil degranulation
Drugs
Diseases		Agammaglobulinemias, including the following six diseases: X-linked agammaglobulinemia (Bruton's agammaglobulinemia, XLA); IgM heavy chain gene deletions; Ig-alpha defect; Autosomal recessive agammaglobulinaemia; B cell-linker protein (BLNK) deficiency; Leucine-rich repeat-containing 8
GWAS			Blood protein levels ( 28240269) Ulcerative colitis ( 28067908)
Interacting Genes		17 interacting genes: BLK BLNK CD19 CD5 CD79B FANCA FATE1 FCAR FYN HCLS1 IGHM JCHAIN LCK LYN PIGR PTPN6 SYK	6 interacting genes: CD79A FCGR1A LYN OSCAR PILRA PPP2CA
Entrez ID		973	2204
HPRD ID		00203	00914
Ensembl ID		ENSG00000105369	ENSG00000186431
Uniprot IDs		P11912	A0A024R4N4 A0A024R4R4 P24071
PDB IDs		1CV9	1OVZ 1OW0 1UCT
Enriched GO Terms of Interacting Partners?
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