CEP57 and KRT13

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		CEP57	KRT13
Description		centrosomal protein 57	keratin 13
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Golgi Apparatus Centrosome Cytosol Microtubule	Nucleus Cytosol Keratin Filament Intermediate Filament Cytoskeleton Extracellular Exosome
	Molecular Function	Protein Binding Microtubule Binding Fibroblast Growth Factor Binding Protein Homodimerization Activity Gamma-tubulin Binding	Structural Molecule Activity Protein Binding
	Biological Process	G2/M Transition Of Mitotic Cell Cycle Spermatid Development Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of G2/M Transition Of Mitotic Cell Cycle Microtubule Anchoring Protein Homooligomerization Ciliary Basal Body-plasma Membrane Docking	Cytoskeleton Organization Keratinization Cornification
Pathways		Regulation of PLK1 Activity at G2/M Transition Loss of Nlp from mitotic centrosomes Recruitment of mitotic centrosome proteins and complexes Loss of proteins required for interphase microtubule organization from the centrosome Recruitment of NuMA to mitotic centrosomes Anchoring of the basal body to the plasma membrane AURKA Activation by TPX2	Keratinization Formation of the cornified envelope
Drugs
Diseases			White sponge nevus
GWAS		Cognitive ability (MTAG) ( 29186694) Erosive tooth wear (severe vs non-severe) ( 29898447) Feeling worry ( 29500382) Intelligence (MTAG) ( 29326435) Rheumatoid arthritis ( 30423114 24390342) Triglyceride levels x loop diuretics use interaction ( 31806883)
Interacting Genes		14 interacting genes: APP FGF2 GCC1 KRT13 KRT15 KRT31 KRT40 MAGEA2B MEGF10 MIA2 MYC RALBP1 TFIP11 UIMC1	52 interacting genes: ABI2 ABI3 AMOTL2 ANKRD36BP1 APC ATP5PO BLOC1S6 C1orf109 C1orf216 C2CD6 CCHCR1 CCNC CEP57 CEP57L1 DNAAF4 EIF4E2 EXOSC5 FANCG FARS2 FBF1 GFAP GOLGA8EP GRAP2 HGS IFT20 KLC3 KLC4 KRT2 KRT20 KRT4 KRT6A KRT6B KRT6C KRT7 KRT71 KRT79 KRT8 LSM2 MOS MYH1 NEFL PPP1R18 PSMB1 PSMB2 RTL8B SGF29 TLE5 TMSB4X TRIM42 TSG101 TXLNA ZNF688
Entrez ID		9702	3860
HPRD ID		16261	01016
Ensembl ID		ENSG00000166037	ENSG00000171401
Uniprot IDs		Q86XR8	A1A4E9 P13646
PDB IDs		4L0R
Enriched GO Terms of Interacting Partners?
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