GTF2IRD1 and KPNA4

Number of citations of the paper that reports this interaction (PubMedID 26275350)
6

Data Source:
BioGRID (two hybrid)

		GTF2IRD1	KPNA4
Description		GTF2I repeat domain containing 1	karyopherin subunit alpha 4
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol	Nuclear Pore Nucleoplasm Cytosol Nuclear Membrane
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding	Protein Binding Nuclear Localization Sequence Binding Nuclear Import Signal Receptor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Multicellular Organism Development Transition Between Slow And Fast Fiber	NLS-bearing Protein Import Into Nucleus Modulation By Virus Of Host Process Response To Hydrogen Peroxide
Pathways			ISG15 antiviral mechanism NS1 Mediated Effects on Host Pathways
Drugs
Diseases
GWAS		Age at suicide ( 31476763) Aluminium levels ( 26025379) General factor of neuroticism ( 30867560) Neuroticism ( 29255261) Severe influenza A (H1N1) infection ( 26379185) SjÃ¶gren's syndrome ( 24097066) Systemic lupus erythematosus ( 26663301 28714469)	Alcohol use disorder (total score) ( 30336701) Bipolar disorder ( 31043756) Pit-and-Fissure caries ( 24556642) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245) Smooth-surface caries ( 24556642) Total cholesterol levels ( 30275531)
Interacting Genes		22 interacting genes: ALMS1 ATP2C1 CDK20 DCAF6 EXOSC4 HDAC3 HTRA4 KPNA1 KPNA2 KPNA3 KPNA4 PIAS1 PIAS2 PIP4P2 PKP1 PKP2 SELENOS SMAD3 SPTLC1 UBC USP20 ZMYM5	20 interacting genes: APP CDKN1B CSE1L CSNK2A1 CUL4B CYHR1 EXO1 GTF2IRD1 HIF1A HNRNPC KPNB1 MAT2B NTRK3 PLAA RAC1 RCC1 RECQL TGM2 TP53 WT1
Entrez ID		9569	3840
HPRD ID		08379	04275
Ensembl ID		ENSG00000006704	ENSG00000186432
Uniprot IDs		E9PFE2 Q9UHL9	O00629
PDB IDs		2D99 2DN5 2DZQ 2DZR	4UAE 5TBK 5XZX 6BVV 6BVZ 6BW9 6BWA 6BWB
Enriched GO Terms of Interacting Partners?
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