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FXR2 and FMR1
Number of citations of the paper that reports this interaction (PubMedID
7489725
)
93
Data Source:
HPRD
(in vivo, in vitro)
FXR2
FMR1
Description
FMR1 autosomal homolog 2
FMRP translational regulator 1
Image
GO Annotations
Cellular Component
Nucleus
Cytoplasm
Cytosol
Polysome
Postsynaptic Density
Membrane
Cytosolic Large Ribosomal Subunit
Axon
Growth Cone
Ribonucleoprotein Granule
Cytoplasmic Ribonucleoprotein Granule
Neuronal Cell Body
Dendritic Spine
Dendritic Spine Neck
Presynapse
Dendritic Filopodium
Chromosome, Centromeric Region
Nucleus
Nucleoplasm
Chromosome
Nucleolus
Cytoplasm
Cytosol
Polysome
MRNA Cap Binding Complex
Chromocenter
Cytoplasmic Stress Granule
Postsynaptic Density
Cajal Body
Membrane
Viral Replication Complex
Extrinsic Component Of Plasma Membrane
Cell Junction
Axon
Dendrite
Growth Cone
Filopodium Tip
SMN Complex
Ribonucleoprotein Granule
Cytoplasmic Ribonucleoprotein Granule
Presynaptic Membrane
Polysomal Ribosome
Cell Projection
Neuron Projection
Neuronal Cell Body
Dendritic Spine
Perikaryon
Axon Terminus
Dendritic Spine Neck
Synapse
Postsynaptic Membrane
Perinuclear Region Of Cytoplasm
Neuronal Ribonucleoprotein Granule
Glial Cell Projection
Presynapse
Postsynapse
Dendritic Filopodium
Messenger Ribonucleoprotein Complex
Growth Cone Filopodium
Ribonucleoprotein Complex
Molecular Function
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Translation Regulator Activity
Protein Heterodimerization Activity
G-quadruplex RNA Binding
Chromatin Binding
RNA Binding
MRNA Binding
MRNA 3'-UTR Binding
Protein Binding
Microtubule Binding
Poly(U) RNA Binding
Translation Repressor Activity
Translation Initiation Factor Binding
RNA Strand Annealing Activity
Poly(G) Binding
Methylated Histone Binding
SiRNA Binding
MiRNA Binding
RNA Stem-loop Binding
Identical Protein Binding
Protein Homodimerization Activity
Ribosome Binding
Ion Channel Binding
Translation Regulator Activity
Protein Heterodimerization Activity
MRNA 5'-UTR Binding
Dynein Complex Binding
Sequence-specific MRNA Binding
Biological Process
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Negative Regulation Of Translation
Regulation Of MRNA Stability
Positive Regulation Of Translation
Regulation Of Filopodium Assembly
Positive Regulation Of Response To DNA Damage Stimulus
Regulation Of Alternative MRNA Splicing, Via Spliceosome
Positive Regulation Of Protein Phosphorylation
Positive Regulation Of Receptor Internalization
MRNA Processing
Cellular Response To DNA Damage Stimulus
Glutamate Receptor Signaling Pathway
RNA Splicing
Viral Process
Negative Regulation Of Translation
Gene Silencing By RNA
Positive Regulation Of Histone Phosphorylation
Cellular Response To UV
Regulation Of MRNA Stability
Modulation By Host Of Viral RNA Genome Replication
Positive Regulation Of Translation
Negative Regulation Of Translational Initiation
Regulation Of Neurotransmitter Secretion
MRNA Transport
Regulation Of Filopodium Assembly
Positive Regulation Of Filopodium Assembly
Regulation Of Gene Silencing By MiRNA
Regulation Of Dendritic Spine Development
Positive Regulation Of Dendritic Spine Development
Cellular Response To Hydroxyurea
Cellular Response To Virus
Regulation Of Neuronal Action Potential
Negative Regulation Of Long-term Synaptic Depression
Positive Regulation Of Intracellular Transport Of Viral Material
Negative Regulation Of Voltage-gated Calcium Channel Activity
Positive Regulation Of Proteasomal Protein Catabolic Process
Negative Regulation Of MRNA Catabolic Process
Positive Regulation Of MRNA Binding
Negative Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Gene Silencing By MiRNA
Negative Regulation Of Cytoplasmic Translation
Positive Regulation Of Response To DNA Damage Stimulus
Pathways
Drugs
Diseases
Premature ovarian failure
Fragile X Syndrome, including: Fragile X Syndrome (FXS); Fragile X tremor/ataxia syndrome (FXTAS)
GWAS
Atrial fibrillation (
30061737
)
IgM levels (
23118916
)
Sex hormone-binding globulin levels (
22675492
)
Antineutrophil cytoplasmic antibody-associated vasculitis (
22808956
)
Fragile X syndrome (
30531935
)
Interacting Genes
101 interacting genes:
AKAP9
AMOTL2
AP1M1
AP2M1
ARL6IP1
BAZ2B
BRCA1
BYSL
C10orf62
C1orf35
CALCOCO2
CAMK2D
CBS
CCDC33
CCDC85B
CDKL3
CEP44
CEP55
COIL
CYFIP1
CYFIP2
DDX17
DMRTB1
DPPA2
DYNLT1
EWSR1
FAM90A1
FBP1
FMR1
FTH1
FXR1
GKAP1
GTSE1
HMBOX1
HNRNPC
KCNRG
KCTD4
KIAA1217
KIF1A
KIF2A
KRT20
KXD1
LASP1
LCMT1
LCP2
LDOC1
MAPRE3
MBIP
MCRS1
MEAF6
MFAP1
MIA3
MORF4L1
MRPL43
NCK2
NDEL1
NDN
NECAB2
NIF3L1
NME1
NONO
NT5C2
PAF1
PAICS
PCBD1
PCM1
PIM1
POM121
PRAM1
PRC1
PSME3
PTS
RABAC1
RALYL
RBBP8
RBM14
RBMX
RBPMS
RPIA
RTN3
RTN4
SCEL
SNAP23
SRPK2
SYT6
SYTL4
TBC1D22B
THAP1
TNNT1
TRAF2
TRIM23
TRIM29
TRIM37
TSC22D4
YES1
ZBTB22
ZBTB8A
ZMAT2
ZNF451
ZNRD2
ZSCAN1
19 interacting genes:
AKAP9
CASK
CYFIP1
CYFIP2
FSD2
FXR1
FXR2
INCA1
MEOX1
NCL
NUFIP1
NUFIP2
RANBP9
RBM14
SF3B2
SPAG5
STAU1
UBE2I
YBX1
Entrez ID
9513
2332
HPRD ID
05629
02398
Ensembl ID
ENSG00000129245
ENSG00000102081
Uniprot IDs
P51116
Q06787
PDB IDs
3H8Z
2BKD
2FMR
2LA5
2QND
4OVA
4QVZ
4QW2
5DE5
5DE8
5DEA
5UWJ
5UWO
Enriched GO Terms of Interacting Partners
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Tagcloud (Intersection)
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