RPH3AL and RAB3D

Number of citations of the paper that reports this interaction (PubMedID 12578829)
52

Data Source:
HPRD (in vitro, in vivo)

		RPH3AL	RAB3D
Description		rabphilin 3A like (without C2 domains)	RAB3D, member RAS oncogene family
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Transport Vesicle Membrane Secretory Granule Membrane	Endosome Cytoplasmic Microtubule Plasma Membrane Synaptic Vesicle Endomembrane System Cytoplasmic Vesicle Vesicle Azurophil Granule Membrane Zymogen Granule Extracellular Exosome Secretory Vesicle
	Molecular Function	Protein Binding Cytoskeletal Protein Binding Rab GTPase Binding LIM Domain Binding Metal Ion Binding	GTPase Activity GTP Binding GTP-dependent Protein Binding Myosin V Binding
	Biological Process	Intracellular Protein Transport Exocytosis Regulation Of Calcium Ion-dependent Exocytosis Positive Regulation Of Insulin Secretion Response To Drug Glucose Homeostasis Negative Regulation Of G Protein-coupled Receptor Signaling Pathway	Intracellular Protein Transport Vesicle Docking Involved In Exocytosis Protein Secretion Regulation Of Exocytosis Peptidyl-cysteine Methylation Rab Protein Signal Transduction Neutrophil Degranulation Bone Resorption Protein Localization To Plasma Membrane Positive Regulation Of Regulated Secretory Pathway
Pathways			Neutrophil degranulation RAB geranylgeranylation
Drugs
Diseases
GWAS		AIDS progression ( 21502085) Dimensional psychopathology (Cognitive) ( 29496196) Idiopathic intracranial hypertension ( 29608535) Impaired insulin sensitivity in response to n-3 PUFA supplementation ( 31779001)	Early cardiac repolarization ( 31600170) HDL cholesterol ( 23505323)
Interacting Genes		13 interacting genes: MID2 RAB27A RAB27B RAB3A RAB3B RAB3C RAB3D RAB3GAP1 RAB8A RIMS2 TCEA3 UNC13B ZYX	12 interacting genes: AKT1 AKT2 AP1M2 APP CEP55 CHM CYP2C9 MAST1 RAB3IP RIMS2 RNF32 RPH3AL
Entrez ID		9501	9545
HPRD ID		05345	05070
Ensembl ID		ENSG00000181031	ENSG00000105514
Uniprot IDs		A8K7D5 Q9UNE2	A0A024R7G2 O95716
PDB IDs			2GF9
Enriched GO Terms of Interacting Partners?
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