MAGED1 and UNC5A

Number of citations of the paper that reports this interaction (PubMedID 12598531)
31

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		MAGED1	UNC5A
Description		MAGE family member D1	unc-5 netrin receptor A
Image		No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Cytoplasm Plasma Membrane Protein-containing Complex	Plasma Membrane Integral Component Of Membrane Intrinsic Component Of Plasma Membrane Neuron Projection Membrane Neuronal Cell Body Membrane Membrane Raft
	Molecular Function	Transcription Coactivator Activity Protein Binding Identical Protein Binding	Netrin Receptor Activity
	Biological Process	Regulation Of Transcription, DNA-templated Regulation Of Transcription By RNA Polymerase II Circadian Regulation Of Gene Expression Regulation Of Circadian Rhythm Regulation Of Apoptotic Process Positive Regulation Of MAP Kinase Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Epithelial Cell Proliferation Positive Regulation Of Branching Involved In Ureteric Bud Morphogenesis Negative Regulation Of Protein Localization To Nucleus Positive Regulation Of Apoptotic Signaling Pathway	Apoptotic Process Axon Guidance Neuron Projection Development Anterior/posterior Axon Guidance Netrin-activated Signaling Pathway
Pathways		NRAGE signals death through JNK Caspase activation via Dependence Receptors in the absence of ligand	Netrin-1 signaling Netrin mediated repulsion signals Caspase activation via Dependence Receptors in the absence of ligand
Drugs
Diseases
GWAS			Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age <50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		62 interacting genes: AKAP9 ARNT2 BAG3 BARD1 BHLHE40 BIRC8 BRCA2 C1orf94 CA8 CCDC33 DAB1 DAZAP2 DLX4 DLX5 EIF3J EIF4E2 EP300 GPR135 GRAP2 HGS HIVEP1 HNRNPLL KPNA2 KRTAP19-5 MAPK3 MDFI MEOX2 MPC1 MSX2 NGFR NOTCH1 NPAS4 NUMBL PITX1 PJA1 PJA2 PLK1 PRKAB2 PSMF1 RBFOX1 RBFOX2 RBM23 RBPMS RFX1 RHOXF2 RNF6 RNF8 ROR2 SIM2 SIRT7 SMAP2 SNRPC TFG TRAF4 TRIM28 TTC23 TTC32 TUBA4A UNC5A XIAP ZNF488 ZNF688	3 interacting genes: DAPK1 MAGED1 NTN1
Entrez ID		9500	90249
HPRD ID		02202	12131
Ensembl ID		ENSG00000179222	ENSG00000113763
Uniprot IDs		Q9Y5V3	H0Y8R2 Q6ZN44
PDB IDs			4V2A
Enriched GO Terms of Interacting Partners?
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