HOMER3 and TRPC1

Number of citations of the paper that reports this interaction (PubMedID 14505576)
145

Data Source:
BioGRID (pull down)

		HOMER3	TRPC1
Description		homer scaffold protein 3	transient receptor potential cation channel subfamily C member 1
Image			No pdb structure
GO Annotations	Cellular Component	Cellular_component Cytoplasm Cytosol Plasma Membrane Postsynaptic Density Cell Junction Dendrite Neuron Projection	Cell Plasma Membrane Integral Component Of Plasma Membrane Cation Channel Complex Receptor Complex
	Molecular Function	Protein Binding G Protein-coupled Glutamate Receptor Binding Identical Protein Binding	Signaling Receptor Binding Cation Channel Activity Calcium Channel Activity Protein Binding Store-operated Calcium Channel Activity ATPase Binding Inositol 1,4,5 Trisphosphate Binding
	Biological Process	Protein Targeting G Protein-coupled Glutamate Receptor Signaling Pathway Negative Regulation Of Interleukin-2 Production Negative Regulation Of Calcineurin-NFAT Signaling Cascade Regulation Of Store-operated Calcium Entry	Calcium Ion Transport Manganese Ion Transport Melanin Biosynthetic Process Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Cytosolic Calcium Ion Concentration Response To Calcium Ion Calcium Ion Transmembrane Transport Regulation Of Cardiac Conduction
Pathways		Neurexins and neuroligins Neurexins and neuroligins	TRP channels Role of second messengers in netrin-1 signaling Ion homeostasis Antigen activates B Cell Receptor (BCR) leading to generation of second messengers
Drugs
Diseases
GWAS
Interacting Genes		31 interacting genes: ABI2 ABI3 APP CEBPB DYNLL2 EAF1 EFHC1 EIF3D FAT1 FRYL GDF15 GRM5 HOMER1 ITPR1 MOS NEBL PAX6 PKN1 POM121 PPP1R18 PRCC PSMA1 PSMA2 PSMC5 RUNX1T1 RYR1 SNRPF SRPK2 TRPC1 USP2 WIPF1	14 interacting genes: BMPR2 CAV1 GRIA1 HOMER1 HOMER3 ITPR2 ITPR3 MDFI MX1 PKD2 RHOA TRPC3 TRPC4 TRPC5
Entrez ID		9454	7220
HPRD ID		07270	11894
Ensembl ID		ENSG00000051128	ENSG00000144935
Uniprot IDs		Q9NSC5	P48995
PDB IDs		2P8V 3CVF
Enriched GO Terms of Interacting Partners?
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