HAND1 and SRA1

Number of citations of the paper that reports this interaction (PubMedID 20398657)
6

Data Source:
BioGRID (far western blotting)

		HAND1	SRA1
Description		heart and neural crest derivatives expressed 1	steroid receptor RNA activator 1
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Nucleolus Cytoplasm RNA Polymerase II Transcription Factor Complex	Nucleus Nucleoplasm Transcription Factor Complex Cytoplasm Cytosol Plasma Membrane Microtubule Cytoskeleton SCAR Complex Cell Leading Edge Intercellular Bridge Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Transcription Coactivator Activity Protein Binding Transcription Factor Binding Enzyme Binding Identical Protein Binding Protein Homodimerization Activity BHLH Transcription Factor Binding Transcription Regulatory Region DNA Binding	Steroid Receptor RNA Activator RNA Binding DNA Binding Transcription Coactivator Activity Protein Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Angiogenesis Mesoderm Formation Blastocyst Development Trophectodermal Cell Differentiation Heart Looping Embryonic Heart Tube Formation Cardiac Left Ventricle Formation Cardiac Right Ventricle Formation Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Heart Development Developmental Process Embryonic Heart Tube Development Odontogenesis Of Dentin-containing Tooth Negative Regulation Of DNA-binding Transcription Factor Activity Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Ventricular Cardiac Muscle Tissue Morphogenesis Cardiac Septum Morphogenesis Mesenchyme Development Cartilage Morphogenesis Trophoblast Giant Cell Differentiation Negative Regulation Of RNA Polymerase II Regulatory Region Sequence-specific DNA Binding	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Regulation Of Mitotic Cell Cycle Cell Differentiation Regulation Of Apoptotic Process Negative Regulation Of Myoblast Differentiation Cellular Response To Estrogen Stimulus Positive Regulation Of Nucleic Acid-templated Transcription
Pathways
Drugs
Diseases
GWAS		Chin dimples ( 27182965) Global electrical heterogeneity phenotypes ( 29622589) Monobrow ( 27182965) QRS complex (Cornell) ( 27659466) QRS duration ( 30679814 27577874 31251759 25035420)	Schizophrenia ( 28991256)
Interacting Genes		15 interacting genes: ACHE DNMT3L FHL2 G3BP1 HAND2 HEY2 HEYL MEF2A MYOD1 PPP2R5D PRKACA PRKCA SRA1 TCF12 TCF3	30 interacting genes: ALX1 ATF1 ATF2 ATF3 ATF4 BLZF1 BTG2 CEBPA CREB1 DDIT3 DMTF1 E2F3 EGR1 EGR2 ESR1 ESR2 ESRRG ETS1 ETS2 FOS FOSB FOSL2 GATA1 GTF2B GTF2H2 GTF3C5 HAND1 NR3C1 TFAP2A UBE2Z
Entrez ID		9421	10011
HPRD ID		03871	18716
Ensembl ID		ENSG00000113196	ENSG00000213523
Uniprot IDs		O96004	Q9HD15
PDB IDs			2MGX 4NBO
Enriched GO Terms of Interacting Partners?
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