TJP2 and EPB41

Number of citations of the paper that reports this interaction (PubMedID 10874042)
44

Data Source:
HPRD (in vitro, two hybrid)

		TJP2	EPB41
Description		tight junction protein 2	erythrocyte membrane protein band 4.1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Plasma Membrane Adherens Junction Bicellular Tight Junction Cell-cell Contact Zone	Cytosol Cytoskeleton Plasma Membrane Cytoplasmic Side Of Plasma Membrane Postsynaptic Density Spectrin-associated Cytoskeleton Basolateral Plasma Membrane Nuclear Body Cell Junction Cortical Cytoskeleton Protein-containing Complex Intercellular Bridge Mitotic Spindle Cell Cortex Region
	Molecular Function	Guanylate Kinase Activity Protein Binding Protein Domain Specific Binding Protein Binding, Bridging Cadherin Binding Protein Tyrosine Kinase Binding	Actin Binding Structural Constituent Of Cytoskeleton Protein Binding Calmodulin Binding 1-phosphatidylinositol Binding Protein C-terminus Binding Spectrin Binding Protein N-terminus Binding Phosphoprotein Binding
	Biological Process	Homotypic Cell-cell Adhesion Hippo Signaling GMP Metabolic Process GDP Metabolic Process Intestinal Absorption Establishment Of Endothelial Intestinal Barrier Regulation Of Membrane Permeability Positive Regulation Of Maintenance Of Permeability Of Blood-brain Barrier	Cell Cycle Regulation Of Cell Shape Actin Cytoskeleton Organization Cortical Actin Cytoskeleton Organization Actomyosin Structure Organization Positive Regulation Of Protein Binding Cell Division Regulation Of Calcium Ion Transport Protein-containing Complex Assembly Regulation Of Intestinal Absorption Positive Regulation Of Protein Localization To Cell Cortex
Pathways		Signaling by Hippo Apoptotic cleavage of cell adhesion proteins	Neurexins and neuroligins
Drugs
Diseases			Hereditary elliptocytosis (HE)
GWAS		Macular thickness ( 30535121) Myopia ( 27182965) Night sleep phenotypes ( 27126917) Refractive error ( 23396134) Renal sinus fat ( 22044751) Spherical equivalent (joint analysis main effects and education interaction) ( 27020472) Spherical equivalent or myopia (age of diagnosis) ( 29808027)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Tourette syndrome ( 30818990)
Interacting Genes		17 interacting genes: CDK6 CGN CLDN1 CLDN2 CLK1 CTNNA1 EPB41 HGS HSPB1 SAFB SCRIB SH3KBP1 SRPK2 TJP1 YWHAB YWHAG YWHAZ	39 interacting genes: ACTA1 APP BCAM C2CD2L CASK CD44 CENPJ CLNS1A CRYAB DLG1 DRD2 DRD3 EGFR EIF3G EPB42 FKBP2 GDI1 GYPC KPNA2 MACROD1 MYL1 NPPA NUMA1 PRKCB RWDD2B SEC14L1 SLC4A1 SMAD3 SPTAN1 SPTB SPTBN1 TJP2 TPM1 TUBA4A U2AF1 U2AF2 YWHAB YWHAQ ZCCHC10
Entrez ID		9414	2035
HPRD ID		06369	00558
Ensembl ID		ENSG00000119139	ENSG00000159023
Uniprot IDs		B7Z2R3 B7Z954 Q9UDY2	A0A2R8Y5G2 A0A2R8Y5Z6 A0A2R8Y6D0 A0A2R8Y7Y3 A0A2U3TZH6 P11171 Q1WWM3 Q29RX4 Q59F12
PDB IDs		2OSG 3E17	1GG3 2RQ1 3QIJ
Enriched GO Terms of Interacting Partners?
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