EFTUD2 and SF3B3

Number of citations of the paper that reports this interaction (PubMedID 22365833)
132

Data Source:
BioGRID (affinity chromatography technology, two hybrid, two hybrid)

		EFTUD2	SF3B3
Description		elongation factor Tu GTP binding domain containing 2	splicing factor 3b subunit 3
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Cajal Body Membrane Nuclear Speck Intracellular Membrane-bounded Organelle U4/U6 X U5 Tri-snRNP Complex U2-type Precatalytic Spliceosome U2-type Catalytic Step 2 Spliceosome Catalytic Step 2 Spliceosome Ribonucleoprotein Complex	Nucleus Nucleoplasm U12-type Spliceosomal Complex Nucleolus U2-type Precatalytic Spliceosome Catalytic Step 2 Spliceosome
	Molecular Function	RNA Binding GTPase Activity Protein Binding GTP Binding U5 SnRNA Binding	Nucleic Acid Binding Protein Binding Protein-containing Complex Binding
	Biological Process	MRNA Splicing, Via Spliceosome Cellular Response To Drug Response To Cocaine	RNA Splicing, Via Transesterification Reactions MRNA Splicing, Via Spliceosome RNA Splicing Negative Regulation Of Protein Catabolic Process
Pathways		mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway	mRNA Splicing - Major Pathway mRNA Splicing - Minor Pathway
Drugs			Quercetin
Diseases
GWAS		Asthma ( 31619474) Craniofacial microsomia ( 26853712)	Hippocampal volume in Alzheimer's disease dementia ( 29274321)
Interacting Genes		12 interacting genes: ARPC3 CYFIP1 GOLM1 GSK3B HINFP LSM8 PIN1 SF3B3 SF3B4 SNRNP200 SREK1 WBP4	29 interacting genes: APBB1 EFTUD2 EPS8 ERG HCK HGS HSPB1 KLF10 MPP3 NAGK NOL12 NUTF2 OSGEP PPIL1 PRPF40A RAD9A RBM6 RUFY2 SF3B1 SMAD5 SNRNP200 SREK1 TAF9 TCERG1 TOE1 WBP4 WWOX YWHAG ZNF579
Entrez ID		9343	23450
HPRD ID		04869	12027
Ensembl ID		ENSG00000108883	ENSG00000189091
Uniprot IDs		B3KX19 Q15029	A8K6V3 Q15393
PDB IDs		3JCR 5MQF 5O9Z 5XJC 5YZG 5Z56 5Z57 5Z58 6AH0 6AHD 6FF4 6FF7 6ICZ 6ID0 6ID1 6QDV 6QW6 6QX9	5IFE 5O9Z 5Z56 5Z57 5Z58 5ZYA 6AH0 6EN4 6FF4 6FF7 6QX9
Enriched GO Terms of Interacting Partners?
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