ZNHIT3 and MEIS2

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

Data Source:
BioGRID (two hybrid)

		ZNHIT3	MEIS2
Description		zinc finger HIT-type containing 3	Meis homeobox 2
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GO Annotations	Cellular Component	Nucleus Cytoplasm Pre-snoRNP Complex	Nuclear Chromatin Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Metal Ion Binding Thyroid Hormone Receptor Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Transcription Coregulator Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding
	Biological Process	Maturation Of LSU-rRNA From Tricistronic RRNA Transcript (SSU-rRNA, 5.8S RRNA, LSU-rRNA) Box C/D SnoRNP Assembly Regulation Of Transcription, DNA-templated SnoRNA Localization	Negative Regulation Of Transcription By RNA Polymerase II Eye Development Transcription By RNA Polymerase II Visual Learning Response To Mechanical Stimulus Pancreas Development Negative Regulation Of Myeloid Cell Differentiation Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription By RNA Polymerase II Response To Growth Factor Positive Regulation Of Cardiac Muscle Myoblast Proliferation
Pathways
Drugs
Diseases
GWAS		Body mass index ( 26426971) Multiple sclerosis ( 31604244) Red cell distribution width ( 27863252 28957414)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Hyperactive-impulsive symptoms ( 18821565) Intraocular pressure ( 24002674) Major depressive disorder ( 27479909) Post bronchodilator FEV1 in COPD ( 26634245) Response to antipsychotic treatment ( 20195266) Restless legs syndrome ( 29029846) Voxel-wise structural brain imaging measurements in Alzheimerâ€™s disease ( 30584014)
Interacting Genes		13 interacting genes: CSNK2A2 ESR2 FCMR HNF4A MBNL1 MEIS2 PBX3 PITX2 PPARG RXRA THRB XRCC3 ZNF24	14 interacting genes: ANXA1 APP ARNT2 C1orf94 CCDC196 DGCR6 HOXA13 HOXA9 OSGIN1 PBX1 RBPMS SQSTM1 TRIM25 ZNHIT3
Entrez ID		9326	4212
HPRD ID		05139	03443
Ensembl ID		ENSG00000273611	ENSG00000134138
Uniprot IDs		A0A024R0X8 Q15649	A0A024R9L4 B3KP81 B3KPD8 B7Z6F6 O14770
PDB IDs		2YQQ 5L85	3K2A 4XRM 5BNG 5EG0
Enriched GO Terms of Interacting Partners?
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