CD9 and CD81

Number of citations of the paper that reports this interaction (PubMedID 8630057)
19

Data Source:
HPRD (in vivo)

		CD9	CD81
Description		CD9 molecule	CD81 molecule
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Space Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Membrane Apical Plasma Membrane Endocytic Vesicle Membrane Clathrin-coated Endocytic Vesicle Membrane Platelet Alpha Granule Membrane Protein-containing Complex Extracellular Exosome Extracellular Vesicle	Immunological Synapse Plasma Membrane Integral Component Of Plasma Membrane Focal Adhesion Membrane Integral Component Of Membrane Basolateral Plasma Membrane Vesicle Extracellular Exosome Tetraspanin-enriched Microdomain
	Molecular Function	Integrin Binding Protein Binding	Virus Receptor Activity Integrin Binding Protein Binding Cholesterol Binding MHC Class II Protein Complex Binding MHC Class II Protein Binding Transferrin Receptor Binding
	Biological Process	Platelet Degranulation Cell Adhesion Fusion Of Sperm To Egg Plasma Membrane Involved In Single Fertilization Brain Development Negative Regulation Of Cell Proliferation Response To Water Deprivation Oligodendrocyte Development Myoblast Fusion Involved In Skeletal Muscle Regeneration Platelet Activation Paranodal Junction Assembly Receptor Internalization Sperm-egg Recognition Negative Regulation Of Cellular Component Movement Cellular Response To Low-density Lipoprotein Particle Stimulus Negative Regulation Of Platelet Aggregation Regulation Of Macrophage Migration	Activation Of MAPK Activity Immunological Synapse Formation Humoral Immune Response Mediated By Circulating Immunoglobulin Positive Regulation Of Inflammatory Response To Antigenic Stimulus Protein Localization Positive Regulation Of Cell Proliferation Myoblast Fusion Involved In Skeletal Muscle Regeneration Regulation Of Complement Activation Positive Regulation Of B Cell Proliferation Receptor Internalization Regulation Of Protein Stability Macrophage Fusion CD4-positive, Alpha-beta T Cell Costimulation Positive Regulation Of 1-phosphatidylinositol 4-kinase Activity Positive Regulation Of Transcription By RNA Polymerase II Viral Entry Into Host Cell Receptor-mediated Virion Attachment To Host Cell Positive Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Immune Response Positive Regulation Of B Cell Receptor Signaling Pathway Positive Regulation Of T Cell Receptor Signaling Pathway Protein Localization To Lysosome Positive Regulation Of Protein Exit From Endoplasmic Reticulum Cellular Response To Low-density Lipoprotein Particle Stimulus Protein Localization To Plasma Membrane Osteoclast Fusion Positive Regulation Of Receptor Clustering Positive Regulation Of Protein Catabolic Process In The Vacuole Regulation Of Macrophage Migration Positive Regulation Of Adaptive Immune Memory Response Positive Regulation Of T-helper 2 Cell Cytokine Production Positive Regulation Of CD4-positive, Alpha-beta T Cell Proliferation Positive Regulation Of T Cell Activation Via T Cell Receptor Contact With Antigen Bound To MHC Molecule On Antigen Presenting Cell
Pathways		Platelet degranulation Acrosome Reaction and Sperm:Oocyte Membrane Binding Uptake and function of diphtheria toxin	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Regulation of Complement cascade
Drugs		C31G
Diseases
GWAS		Colorectal cancer ( 24836286) Colorectal cancer or advanced adenoma ( 30510241) Mean platelet volume ( 22139419 27863252) Paclitaxel-induced neuropathy ( 23776197) Platelet count ( 26805783 22139419)
Interacting Genes		22 interacting genes: ADAM2 ADRB2 CD19 CD36 CD38 CD53 CD59 CD63 CD81 CLN8 HBEGF IGSF8 ITGA2 ITGA3 ITGA5 ITGB1 KIT PRKCA PTGFRN SERPINH1 TSPAN4 VKORC1	23 interacting genes: ADRB2 CD19 CD9 CSNK2B DLG5 GLP1R HNRNPD IFITM1 IGSF8 INO80B ITGA4 JAK3 KIT LMNA MYOC PTGFRN RBBP6 RNF128 SHC1 SIRPA TSPAN4 VKORC1 ZBTB16
Entrez ID		928	975
HPRD ID		00880	08924
Ensembl ID		ENSG00000010278	ENSG00000110651
Uniprot IDs		A6NNI4 B4DK09 P21926	A0A024RCB7 E9PJK1 P60033
PDB IDs			1G8Q 1IV5 2AVZ 3X0E 5DFV 5DFW 5M2C 5M33 5M3D 5M3T 5M4R 5TCX 6EJG 6EJM 6EK2
Enriched GO Terms of Interacting Partners?
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