FAM114A1 and SPG21

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

		FAM114A1	SPG21
Description		family with sequence similarity 114 member A1	SPG21 abhydrolase domain containing, maspardin
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Golgi Apparatus Cytosol	Golgi Apparatus Cytosol Endosome Membrane Trans-Golgi Network Transport Vesicle Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Protein Binding CD4 Receptor Binding
	Biological Process		Antigen Receptor-mediated Signaling Pathway
Pathways
Drugs
Diseases			Hereditary spastic paraplegia (SPG)
GWAS		Alcohol dependence ( 24166409) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic sensitization ( 23817571) Asthma or allergic disease (pleiotropy) ( 29785011) Helicobacter pylori serologic status ( 23652523) Mean corpuscular volume ( 27863252) Moderate or severe diarrhoea in darapladib-treated cardiovascular disease (time to event) ( 28753643)
Interacting Genes		6 interacting genes: AGTRAP CMTM5 RAB2A RAB2B SPG21 TNS2	37 interacting genes: AGTRAP AKIRIN2 ARL6IP1 CCDC102B CCDC33 CD4 CMTM5 CRYAA CTPS2 CUTC DTX2 DTX3L EFHC2 FAM114A1 GGA2 GSK3A IKZF3 INCA1 KRT15 LMNA MID2 MTMR9 PRPS1 RABAC1 REEP6 RTN4 S100B SPRED2 TCF12 TCF4 TFG TRAF1 TRAF2 TRIM23 TRIM54 TRIM9 ZNF263
Entrez ID		92689	51324
HPRD ID		11282	10492
Ensembl ID		ENSG00000197712	ENSG00000090487
Uniprot IDs		A1MMZ0 Q8IWE2	A0A024R5Y1 Q9NZD8
PDB IDs
Enriched GO Terms of Interacting Partners?
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