ZW10 and RINT1

Number of citations of the paper that reports this interaction (PubMedID 15029241)
79

Data Source:
HPRD (two hybrid, in vitro, in vivo)

		ZW10	RINT1
Description		zw10 kinetochore protein	RAD50 interactor 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Kinetochore Condensed Chromosome Kinetochore Spindle Pole Cell Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Kinetochore Microtubule Cytosol Membrane Dsl1/NZR Complex RZZ Complex	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Cytosol Dsl1/NZR Complex
	Molecular Function	Protein Binding Centromeric DNA Binding	Protein Binding
	Biological Process	Mitotic Sister Chromatid Segregation Establishment Of Mitotic Spindle Orientation ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Mitotic Metaphase Plate Congression Mitotic Cell Cycle Checkpoint Mitotic Spindle Assembly Checkpoint Regulation Of Exit From Mitosis Protein Transport Protein Localization To Kinetochore Cell Division Meiotic Cell Cycle Protein-containing Complex Assembly	Retrograde Vesicle-mediated Transport, Golgi To ER Cell Cycle Protein Transport Regulation Of ER To Golgi Vesicle-mediated Transport Regulation Of Signal Transduction Involved In Mitotic G2 DNA Damage Checkpoint
Pathways		Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal Separation of Sister Chromatids Resolution of Sister Chromatid Cohesion RHO GTPases Activate Formins COPI-dependent Golgi-to-ER retrograde traffic Mitotic Prometaphase EML4 and NUDC in mitotic spindle formation	COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Parental longevity (father's attained age) ( 29227965)
Interacting Genes		7 interacting genes: APP DCTN2 PIAS4 PTF1A RINT1 ZWILCH ZWINT	55 interacting genes: ARNT2 BNIP3L C1orf109 CCDC121 CCDC146 CEP57L1 CSPP1 CWF19L2 DCX EPC1 FAM107A FAM110A FAM124B FAM161A FAM81B FAM90A1 FANCG GFI1B GRAP2 HDAC4 HGS LMO2 LSP1P3 MCM7 PCM1 PIK3R2 PIMREG PRPF31 PSTPIP1 RAD50 RB1 RBL1 RBL2 RBM41 RIBC1 RNF6 RSRC2 RTP5 SCNM1 SFR1 SGF29 SH2D4A SMARCB1 SMARCE1 SNW1 SPTBN1 STRN TEX9 TXLNA VPS37C XPNPEP1 ZNF655 ZNF688 ZNF697 ZW10
Entrez ID		9183	60561
HPRD ID		04902	15250
Ensembl ID		ENSG00000086827	ENSG00000135249
Uniprot IDs		O43264	Q6NUQ1
PDB IDs
Enriched GO Terms of Interacting Partners?
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