YTHDC1 and EDC4

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		YTHDC1	EDC4
Description		YTH domain containing 1	enhancer of mRNA decapping 4
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Plasma Membrane Nuclear Speck	P-body Nucleus Nucleoplasm Cytoplasm Cytosol Membrane Cytoplasmic Ribonucleoprotein Granule
	Molecular Function	RNA Binding Protein Binding N6-methyladenosine-containing RNA Binding	Protein Binding
	Biological Process	MRNA Splice Site Selection MRNA Export From Nucleus Dosage Compensation By Inactivation Of X Chromosome Posttranscriptional Regulation Of Gene Expression Regulation Of MRNA Splicing, Via Spliceosome	Biological_process Deadenylation-independent Decapping Of Nuclear-transcribed MRNA Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay
Pathways			mRNA decay by 5' to 3' exoribonuclease
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	HDL cholesterol ( 21347282) Metabolic syndrome ( 22399527) Schizophrenia ( 25056061 29483656)
Interacting Genes		35 interacting genes: ABL1 ADAMTS4 CFH CLK1 CLK2 CORO1A DVL3 EDC4 EMD FYN GOLGA2 HNRNPK KHDRBS1 KHDRBS2 KHDRBS3 KRT18 LAMC3 LAMTOR5 LZTS2 MPRIP PLG PROSER2 RBMY1F SDCBP2 SEPTIN10 SOX13 SRC SRPK1 SRPK2 SRSF1 SRSF2 TRA2A TRA2B TXK VPS51	5 interacting genes: CCL5 EIF2AK2 FBLN1 GIT2 YTHDC1
Entrez ID		91746	23644
HPRD ID		11689	06911
Ensembl ID		ENSG00000083896	ENSG00000038358
Uniprot IDs		J3QR07 Q96MU7	Q6P2E9
PDB IDs		2YUD 4R3H 4R3I 6RT4 6RT5 6RT6 6RT7
Enriched GO Terms of Interacting Partners?
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Tagcloud (Difference) ?
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