IL1RL1 and HYOU1

		IL1RL1	HYOU1
Description		interleukin 1 receptor like 1	hypoxia up-regulated 1
Image			No pdb structure
GO Annotations	Cellular Component	Extracellular Region Cytosol Plasma Membrane Focal Adhesion External Side Of Plasma Membrane Integral Component Of Membrane	Extracellular Region Endoplasmic Reticulum Endoplasmic Reticulum Lumen Smooth Endoplasmic Reticulum Focal Adhesion Membrane Endoplasmic Reticulum Chaperone Complex Extracellular Exosome Endocytic Vesicle Lumen
	Molecular Function	Interleukin-33 Binding Interleukin-33 Receptor Activity Cytokine Receptor Activity Interleukin-1 Receptor Activity Protein Binding NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	Protein Binding ATP Binding Chaperone Binding
	Biological Process	Negative Regulation Of T-helper 1 Type Immune Response Immune Response Signal Transduction Negative Regulation Of Interferon-gamma Production Positive Regulation Of Interleukin-5 Production Interleukin-33-mediated Signaling Pathway Positive Regulation Of Macrophage Activation Positive Regulation Of Inflammatory Response Positive Regulation Of Chemokine Secretion	Response To Ischemia ER To Golgi Vesicle-mediated Transport Receptor-mediated Endocytosis Response To Endoplasmic Reticulum Stress IRE1-mediated Unfolded Protein Response Cellular Response To Hypoxia Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway
Pathways		PIP3 activates AKT signaling PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling Interleukin-33 signaling	Scavenging by Class F Receptors Scavenging by Class F Receptors XBP1(S) activates chaperone genes
Drugs
Diseases
GWAS		Adult asthma ( 30578877) Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic rhinitis ( 30013184 31361310) Allergic sensitization ( 30013184 23817571) Allergy ( 27182965) Asthma ( 23028483 21804549 31361310 30929738 27182965 31619474 26620591 29273806) Asthma (adult onset) ( 31036433) Asthma (childhood onset) ( 31036433 30929738 29273806) Asthma (moderate or severe) ( 30552067) Asthma (time to onset) ( 27130862) Asthma and hay fever ( 24388013) Asthma onset (childhood vs adult) ( 30929738) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 26482879) Blood protein levels ( 30072576 29875488 28240269) Blood protein levels in cardiovascular risk ( 28369058) Celiac disease ( 20190752 18311140) Crohn's disease ( 28067908 21102463) Delirium ( 29631748) Eosinophil counts ( 29403010 19198610) FEV1 ( 30804560) Inflammatory bowel disease ( 28067908 23128233) Lung function (FEV1/FVC) ( 30804560) Nasal polyps ( 30643255) Primary biliary cholangitis ( 26394269) Self-reported allergy ( 23817569) Serum protein levels (sST2) ( 23999434) Waist circumference ( 23966867)	Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		8 interacting genes: APP CLEC7A HRAS HYOU1 IL33 MYD88 TIRAP TMED1	12 interacting genes: CADM1 DPYSL3 IL1R1 IL1RL1 INPPL1 NXPE4 PPP2R1B RBM7 SEL1L TAGLN TMEM245 TP53BP2
Entrez ID		9173	10525
HPRD ID		03123	03448
Ensembl ID		ENSG00000115602	ENSG00000149428
Uniprot IDs		Q01638	A0A384P5T6 A0A494C039 B3KXH0 B7Z602 B7Z766 Q6IN67 Q9Y4L1
PDB IDs		4KC3
Enriched GO Terms of Interacting Partners?
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