ANKRD40 and AHCY

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, affinity chromatography technology, two hybrid, affinity chromatography technology)

		ANKRD40	AHCY
Description		ankyrin repeat domain 40	adenosylhomocysteinase
Image		No pdb structure
GO Annotations	Cellular Component	Cellular_component	Nucleus Cytosol Melanosome Neuron Projection Extracellular Exosome
	Molecular Function	Molecular_function Protein Binding	Adenosylhomocysteinase Activity Protein Binding Adenyl Nucleotide Binding Identical Protein Binding NAD Binding
	Biological Process	Biological_process	Sulfur Amino Acid Metabolic Process Response To Hypoxia Chronic Inflammatory Response To Antigenic Stimulus One-carbon Metabolic Process Response To Nutrient S-adenosylhomocysteine Catabolic Process Methylation S-adenosylmethionine Cycle Circadian Sleep/wake Cycle
Pathways			Methylation Sulfur amino acid metabolism Metabolism of ingested SeMet, Sec, MeSec into H2Se Defective AHCY causes Hypermethioninemia with S-adenosylhomocysteine hydrolase deficiency (HMAHCHD)
Drugs			Isopropyl Alcohol (1'r,2's)-9-(2-Hydroxy-3'-Keto-Cyclopenten-1-Yl)Adenine 3'-Oxo-Adenosine D-Eritadenine Copper
Diseases			Hypermethioninemia; Methionine adenosyltransferase deficiency; S-adenosylhomocysteine hydrolase deficiency
GWAS			Heel bone mineral density ( 30598549) Height ( 28552196) Vitiligo ( 27723757)
Interacting Genes		4 interacting genes: AHCY PIN1 RAD23A SDCBP	7 interacting genes: ANKRD40 APPBP2 C1orf50 POT1 PXN TERF1 YWHAQ
Entrez ID		91369	191
HPRD ID		17502	01621
Ensembl ID		ENSG00000154945	ENSG00000101444
Uniprot IDs		A8IK34 Q6AI12	A0A384MTQ3 P23526 Q1RMG2
PDB IDs			1A7A 1LI4 3NJ4 4PFJ 4PGF 4YVF 5W49 5W4B
Enriched GO Terms of Interacting Partners?
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