MTA1 and SAT1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		MTA1	SAT1
Description		metastasis associated 1	spermidine/spermine N1-acetyltransferase 1
Image
GO Annotations	Cellular Component	Nucleus Nuclear Envelope Nucleoplasm Cytoplasm Cytosol Microtubule NuRD Complex Intracellular Membrane-bounded Organelle	Intracellular Cytosol
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding RNA Polymerase II Repressing Transcription Factor Binding Chromatin Binding Transcription Coactivator Activity Transcription Corepressor Activity Protein Binding Zinc Ion Binding Histone Deacetylase Binding	Diamine N-acetyltransferase Activity Protein Binding N-acetyltransferase Activity Spermidine Binding Identical Protein Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Double-strand Break Repair Signal Transduction Response To Ionizing Radiation Histone Deacetylation Circadian Regulation Of Gene Expression Regulation Of Gene Expression, Epigenetic Entrainment Of Circadian Clock By Photoperiod Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Locomotor Rhythm Positive Regulation Of Protein Autoubiquitination Positive Regulation Of Nucleic Acid-templated Transcription	Angiogenesis Polyamine Biosynthetic Process Putrescine Catabolic Process Spermidine Acetylation Regulation Of Cell Proliferation
Pathways		HDACs deacetylate histones SUMOylation of transcription factors ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression RNA Polymerase I Transcription Initiation Regulation of PTEN gene transcription Regulation of PTEN gene transcription	Interconversion of polyamines
Drugs			N-ethyl-N-[3-(propylamino)propyl]propane-1,3-diamine
Diseases			Keratosis follicularis spinulosa decalvans
GWAS		Heel bone mineral density ( 30598549)
Interacting Genes		38 interacting genes: BCL11A BLOC1S1 CCNH CSNK1G2 DDX18 DYNLL1 E2F1 ESR1 FHL3 GPR183 GRB2 H3-4 HDAC1 HDAC2 HIF1A ITGB3BP JUN KHDRBS2 KRT40 KRTAP10-8 LMO4 LRRK2 LZTS2 MAGEA11 MBD3L2 MNAT1 NACC2 NELFCD NOTCH2NLA RBBP4 SAT1 SH3GL1 SH3GLB1 SUMO2 TEX11 TP53 TRIM25 UBE2I	76 interacting genes: ABCB8 APLP1 B4GALT3 C19orf25 CASP7 CCDC148 CCDC90B CCHCR1 CEP126 CHD3 COPS6 CRMP1 CSNK2A1 CSNK2A2 DDX39A DGKZ DIPK1B DMRT3 DNPEP EEF1G EIF3D EPHB6 ERG28 EVA1A FAM156A FAM86C1P FTSJ3 FUNDC2 GBP2 GDF9 HIF1A HOXB6 HOXB9 HSPB1 HSPE1 INO80C ITGA9 JUNB KAT5 KAT7 KCNA4 LNX1 LRIF1 LUC7L2 MED31 MRPL9 MTA1 NIF3L1 NMRK2 PLGRKT PRDX2 PTN RACK1 RBM17 RBM48 REL RELA RPLP1 SARAF SAT2 SEPHS1 SETDB1 SNAI2 TACO1 TCF25 TLE1 TP53 TP53TG1 TSC22D4 TUBB2A UBE2D3 UNC119 UTP14A VASP VKORC1 ZHX1
Entrez ID		9112	6303
HPRD ID		04633	02431
Ensembl ID		ENSG00000182979	ENSG00000130066
Uniprot IDs		Q13330 Q9BRL8	A0A384NQ10 P21673
PDB IDs		4BKX 4PBY 4PBZ 4PC0 5FXY 5ICN 6G16	2B3U 2B3V 2B4B 2B4D 2B58 2B5G 2F5I 2FXF 2G3T 2JEV
Enriched GO Terms of Interacting Partners?
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