USP6 and ATXN7L3

Number of citations of the paper that reports this interaction (PubMedID 16713569)
313

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		USP6	ATXN7L3
Description		ubiquitin specific peptidase 6	ataxin 7 like 3
Image		No pdb structure
GO Annotations	Cellular Component	Cytoplasm Lysosome Plasma Membrane Recycling Endosome	SAGA Complex Nucleus DUBm Complex
	Molecular Function	Nucleic Acid Binding Cysteine-type Endopeptidase Activity Thiol-dependent Ubiquitin-specific Protease Activity GTPase Activator Activity Protein Binding Calmodulin Binding Rab GTPase Binding	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Nuclear Receptor Transcription Coactivator Activity
	Biological Process	Cellular Protein Modification Process Ubiquitin-dependent Protein Catabolic Process Intracellular Protein Transport Protein Deubiquitination Regulation Of Vesicle-mediated Transport Activation Of GTPase Activity	Histone Monoubiquitination Histone Deubiquitination Positive Regulation Of Transcription, DNA-templated
Pathways			HATs acetylate histones
Drugs
Diseases
GWAS		PEG-asparaginase hypersensitivity without enzyme activity in childhood acute lymphoblastic leukaemia ( 30450575)	Bipolar disorder ( 31043756) Height ( 31562340)
Interacting Genes		14 interacting genes: ANKRD44 APP ATXN7L3 CALM2 CDC42 EXOSC8 JAK1 JUN MDFI MYL2 RAB33B RAC1 TFIP11 UBC	11 interacting genes: APP DCAKD ENY2 H2AC20 H2BC21 PICK1 SECISBP2 SERTAD1 UBC UCHL3 USP6
Entrez ID		9098	56970
HPRD ID		06827	12507
Ensembl ID		ENSG00000129204	ENSG00000087152
Uniprot IDs		P35125	Q14CW9
PDB IDs			2KKT
Enriched GO Terms of Interacting Partners?
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