LDB2 and LHX9

Number of citations of the paper that reports this interaction (PubMedID 9880598)
39

Data Source:
HPRD (in vitro)

		LDB2	LHX9
Description		LIM domain binding 2	LIM homeobox 9
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Factor Complex Nucleolus Plasma Membrane Cell Leading Edge	Nuclear Chromatin Nucleus
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Coregulator Activity Protein Binding Enzyme Binding LIM Domain Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Transcription Corepressor Activity Protein Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Hair Follicle Development Multicellular Organism Development Epithelial Structure Maintenance Regulation Of Cell Migration Somatic Stem Cell Population Maintenance Regulation Of Kinase Activity Positive Regulation Of Cellular Component Biogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II	Cell Proliferation Male Gonad Development Female Gonad Development Neuron Differentiation Gonad Morphogenesis Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Dorsal Spinal Cord Interneuron Anterior Axon Guidance
Pathways			Regulation of expression of SLITs and ROBOs
Drugs
Diseases
GWAS		Change in LVEF in response to paclitaxel and trastuzumab in HER2+ breast cancer ( 28763429) Number of sexual partners ( 30643258) QT interval ( 23534349) Rhegmatogenous retinal detachment ( 23585552) Systemic juvenile idiopathic arthritis ( 27927641) Waist circumference ( 28552196)	General risk tolerance (MTAG) ( 30643258) Heel bone mineral density ( 30598549)
Interacting Genes		12 interacting genes: ISL1 LHX4 LHX9 LMO3 LMO4 RASIP1 RILP RLIM SSBP2 SSBP3 SSBP4 TSNAX	5 interacting genes: CWF19L2 KHK LDB2 SMAD2 SMURF1
Entrez ID		9079	56956
HPRD ID		16022	07299
Ensembl ID		ENSG00000169744	ENSG00000143355
Uniprot IDs		B7Z6D0 E9PFI4 G5E9Y7 O43679	H0YL54 Q9NQ69
PDB IDs			2DMQ
Enriched GO Terms of Interacting Partners?
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