FATE1 and SLC7A1

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		FATE1	SLC7A1
Description		fetal and adult testis expressed 1	solute carrier family 7 member 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Mitochondrial Outer Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Integral Component Of Membrane Mitochondria-associated ER Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Protein-containing Complex
	Molecular Function	Protein Binding Ubiquitin Protein Ligase Binding	L-ornithine Transmembrane Transporter Activity Protein Binding Amino Acid Transmembrane Transporter Activity Arginine Transmembrane Transporter Activity L-lysine Transmembrane Transporter Activity
	Biological Process	Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Mitochondrial Calcium Ion Concentration	Amino Acid Transport L-arginine Import Across Plasma Membrane L-ornithine Transmembrane Transport L-lysine Transmembrane Transport
Pathways			Amino acid transport across the plasma membrane
Drugs			L-Lysine L-Arginine Ornithine
Diseases
GWAS		Systemising ( 31508503)	Blood osmolality (transformed sodium) ( 28360221) Diastolic blood pressure ( 27841878) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (diuretics) ( 31015401) Metabolite levels ( 23823483) Systolic blood pressure ( 27841878 30578418)
Interacting Genes		57 interacting genes: AGTRAP AQP9 ATCAY BCL2L2 BIK BNIP2 BNIP3 BNIP3L BSND BTN2A2 CCDC70 CD302 CD79A CSF2RA CXCR3 DCTN5 EMD GPR25 INPP5K KASH5 KCNS2 LMNA LNPEP MARCHF2 MARCHF5 MR1 NDUFB11 NRG4 NRSN1 OCLN PIN4 PRRG2 RNF183 RPRM SEC22A SEC22C SEC23B SLC38A1 SLC7A1 SMIM14 SNAP47 SYNDIG1 SYNE4 SYNGR1 SYNGR2 SYNPR TBP TIMMDC1 TM4SF4 TMEM11 TMEM74 TRAF2 TRAF3IP3 USHBP1 USP20 YIPF2 YIPF4	3 interacting genes: APP FATE1 LMNA
Entrez ID		89885	6541
HPRD ID		02346	00091
Ensembl ID		ENSG00000147378	ENSG00000139514
Uniprot IDs		Q969F0	A0A024RDQ9 P30825
PDB IDs
Enriched GO Terms of Interacting Partners?
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