PLOD3 and EFHC2

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid, two hybrid)

		PLOD3	EFHC2
Description		procollagen-lysine,2-oxoglutarate 5-dioxygenase 3	EF-hand domain containing 2
Image
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum Membrane Rough Endoplasmic Reticulum Golgi Apparatus Trans-Golgi Network Collagen-containing Extracellular Matrix Extracellular Exosome	Microtubule
	Molecular Function	Iron Ion Binding Protein Binding Procollagen-lysine 5-dioxygenase Activity L-ascorbic Acid Binding Procollagen Glucosyltransferase Activity Procollagen Galactosyltransferase Activity	Calcium Ion Binding Protein Binding
	Biological Process	In Utero Embryonic Development Endothelial Cell Morphogenesis Protein O-linked Glycosylation Protein Localization Peptidyl-lysine Hydroxylation Neural Tube Development Collagen Fibril Organization Cellular Response To Hormone Stimulus Collagen Metabolic Process Vasodilation Hydroxylysine Biosynthetic Process Epidermis Morphogenesis Oxidation-reduction Process Lung Morphogenesis Basement Membrane Assembly	Regulation Of Neuron Projection Development Cellular Response To Leukemia Inhibitory Factor
Pathways		Collagen biosynthesis and modifying enzymes
Drugs		Vitamin C Succinic acid
Diseases
GWAS		Blood protein levels ( 30072576)	Mean arterial pressure ( 29403010)
Interacting Genes		9 interacting genes: CCDC85B DPPA2 EFHC2 EHMT2 FAM153A LINC00839 RAB3IP RHOU RHOXF2	37 interacting genes: ARHGEF5 ARMC7 CACNB4 CCDC120 CCHCR1 CCNG2 CDKN2A CLIC3 COPE CYFIP1 DGCR6 EDC3 EFHC1 EGLN3 EMD EXOC8 FAM107A HNRNPLL JAKMIP2 KIF9 LONRF1 MAPK9 NCDN NCK2 NDOR1 NR3C1 PBLD PLOD3 PTK6 RAD51D RUNX1T1 SNRNP25 SPG21 STK16 TRIM42 TSSK3 TUBGCP4
Entrez ID		8985	80258
HPRD ID		04347	06540
Ensembl ID		ENSG00000106397	ENSG00000183690
Uniprot IDs		O60568 Q9UG85	Q5JST6
PDB IDs		6FXK 6FXM 6FXR 6FXT 6FXX 6FXY	2Z13 2Z14
Enriched GO Terms of Interacting Partners?
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