AP3D1 and VAMP7

Number of citations of the paper that reports this interaction (PubMedID 12853575)
73

Data Source:
HPRD (in vitro, in vivo, two hybrid)

		AP3D1	VAMP7
Description		adaptor related protein complex 3 subunit delta 1	vesicle associated membrane protein 7
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GO Annotations	Cellular Component	Golgi Membrane Cell Lysosomal Membrane Golgi Apparatus Endosome Membrane Membrane AP-3 Adaptor Complex Terminal Bouton Postsynapse Presynaptic Endosome Glutamatergic Synapse Axon Cytoplasm	Cell Cytoplasm Lysosomal Membrane Endoplasmic Reticulum Membrane Trans-Golgi Network Plasma Membrane Cell Surface Membrane Lamellipodium Cell Junction Secretory Granule Filopodium Integral Component Of Synaptic Vesicle Membrane Clathrin-coated Vesicle Membrane Secretory Granule Membrane Phagocytic Vesicle Membrane Platelet Alpha Granule Pseudopodium SNARE Complex Late Endosome Membrane Azurophil Granule Membrane Neuron Projection Intracellular Membrane-bounded Organelle Apical Part Of Cell Phagocytic Vesicle Perinuclear Region Of Cytoplasm Extracellular Exosome Hippocampal Mossy Fiber To CA3 Synapse
	Molecular Function	Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding Syntaxin Binding
	Biological Process	Protein Targeting To Vacuole Intracellular Protein Transport Golgi To Vacuole Transport Anterograde Axonal Transport Synaptic Vesicle Budding From Endosome Melanosome Organization Endosome To Melanosome Transport Antigen Processing And Presentation, Exogenous Lipid Antigen Via MHC Class Ib Anterograde Synaptic Vesicle Transport Synaptic Vesicle Membrane Organization Positive Regulation Of NK T Cell Differentiation Regulation Of Sequestering Of Zinc Ion Protein Localization To Membrane Neurotransmitter Receptor Transport, Postsynaptic Endosome To Lysosome	Exocytosis ER To Golgi Vesicle-mediated Transport Post-Golgi Vesicle-mediated Transport Vesicle Fusion Phagocytosis, Engulfment Endosome To Lysosome Transport Vesicle-mediated Transport Calcium Ion Regulated Exocytosis Triglyceride Transport SNARE Complex Assembly Golgi To Plasma Membrane Protein Transport Eosinophil Degranulation Neutrophil Degranulation Natural Killer Cell Degranulation Vesicle Transport Along Microtubule Vesicle Fusion With Golgi Apparatus Positive Regulation Of Dendrite Morphogenesis Membrane Organization Autophagosome Maturation Regulation Of Protein Targeting To Vacuolar Membrane Positive Regulation Of Histamine Secretion By Mast Cell
Pathways			trans-Golgi Network Vesicle Budding Lysosome Vesicle Biogenesis Golgi Associated Vesicle Biogenesis Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis Interleukin-12 signaling
Drugs
Diseases
GWAS		Height ( 28552196 31562340) Hematocrit ( 27863252) Hemoglobin concentration ( 27863252) Myocardial infarction ( 24916648) Pulse pressure ( 30578418) Red blood cell count ( 27863252) Systolic blood pressure ( 30578418)
Interacting Genes		10 interacting genes: AP3B1 AP3S1 AP3S2 ARF1 ARF6 CCN2 RUFY1 SLC30A3 VAMP7 VPS41	11 interacting genes: AGFG1 ANKRD27 AP3D1 DNAJC5 SNAP23 SNAP25 SNAP29 STX1A STX3 STX4 STX7
Entrez ID		8943	6845
HPRD ID		06260	02084
Ensembl ID		ENSG00000065000	ENSG00000124333
Uniprot IDs		O14617	A0A024R061 A0A024R074 P51809
PDB IDs		4AFI	2DMW
Enriched GO Terms of Interacting Partners?
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