MBD2 and MBD3L1

Number of citations of the paper that reports this interaction (PubMedID 15456747)
25

Data Source:
HPRD (in vivo, two hybrid, in vitro)

		MBD2	MBD3L1
Description		methyl-CpG binding domain protein 2	methyl-CpG binding domain protein 3 like 1
Image			No pdb structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Nuclear Chromatin Heterochromatin Nucleus Nucleoplasm Cytosol Protein-containing Complex	Nucleus
	Molecular Function	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding Satellite DNA Binding MRNA Binding Protein Binding Methyl-CpG Binding Protein Domain Specific Binding Nucleosomal DNA Binding SiRNA Binding C2H2 Zinc Finger Domain Binding	Protein Binding Methyl-CpG Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Chromatin Silencing At RDNA Methylation-dependent Chromatin Silencing Heart Development Aging Response To Mechanical Stimulus Positive Regulation Of Wnt Signaling Pathway Response To Nutrient Levels Response To Estradiol Cellular Protein-containing Complex Assembly Positive Regulation Of Chromatin Binding Regulation Of Cell Proliferation Maternal Behavior ATP-dependent Chromatin Remodeling Regulation Of DNA Methylation Negative Regulation Of Transcription, DNA-templated Embryonic Organ Development Cellular Response To Organic Cyclic Compound	Negative Regulation Of Transcription By RNA Polymerase II Methylation-dependent Chromatin Silencing
Pathways		NoRC negatively regulates rRNA expression RNA Polymerase I Promoter Opening
Drugs
Diseases
GWAS		Nickel levels ( 26025379) Periodontitis (Mean PAL) ( 24024966) Prostate cancer ( 29892016) Psoriasis ( 23143594)
Interacting Genes		15 interacting genes: CREBBP DHX9 GATAD2A GATAD2B GPN1 HDAC1 HDAC2 HINFP LAMTOR3 MBD3 MBD3L1 MBD3L2 RBBP4 SIN3A TBP	3 interacting genes: MBD2 MBD3 TIMM29
Entrez ID		8932	85509
HPRD ID		04647	12138
Ensembl ID		ENSG00000134046	ENSG00000170948
Uniprot IDs		A0A024R2B8 Q9UBB5	Q8WWY6
PDB IDs		2L2L 6C1A 6C1T 6C1U 6C1V 6C2F 6CNP 6CNQ
Enriched GO Terms of Interacting Partners?
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