LDB1 and CTDSP1

Number of citations of the paper that reports this interaction (PubMedID 14743429)
4

Data Source:
HPRD (in vitro, in vivo)

		LDB1	CTDSP1
Description		LIM domain binding 1	CTD small phosphatase 1
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GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Transcription Factor Complex Cell Leading Edge Protein-containing Complex Beta-catenin-TCF Complex	Nucleus Nucleoplasm Extracellular Exosome
	Molecular Function	RNA Polymerase II Activating Transcription Factor Binding Transcription Corepressor Activity Protein Binding Enzyme Binding LIM Domain Binding Protein Homodimerization Activity	Phosphoprotein Phosphatase Activity Protein Binding RNA Polymerase II CTD Heptapeptide Repeat Phosphatase Activity Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Transcription-dependent Tethering Of RNA Polymerase II Gene DNA At Nuclear Periphery Transcription, DNA-templated Regulation Of Transcription, DNA-templated Multicellular Organism Development Neuron Differentiation Regulation Of Cell Migration Regulation Of DNA-templated Transcription, Elongation Regulation Of Kinase Activity Histone H3-K4 Acetylation Negative Regulation Of Erythrocyte Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Hemoglobin Biosynthetic Process Regulation Of Focal Adhesion Assembly Regulation Of Hematopoietic Stem Cell Differentiation	Negative Regulation Of Protein Phosphorylation Regulation Of Transcription By RNA Polymerase II Protein Dephosphorylation Negative Regulation Of Neuron Differentiation Negative Regulation Of G1/S Transition Of Mitotic Cell Cycle
Pathways		RUNX1 regulates transcription of genes involved in differentiation of HSCs Regulation of expression of SLITs and ROBOs
Drugs			Aspartate Beryllium Trifluoride Citric Acid
Diseases
GWAS		General cognitive ability ( 29844566) Intelligence (MTAG) ( 29326435) Pulse pressure ( 30578418)	Inflammatory bowel disease ( 23128233) Mean corpuscular hemoglobin concentration ( 27863252)
Interacting Genes		27 interacting genes: ATXN1 CTDSP1 DNMT3L ESR1 IRAK3 ISL1 LHX2 LHX3 LHX8 LMO1 LMO2 LMO3 LMO4 LMX1A LMX1B LSM7 POLR1B PSMA1 PSMD10 RLIM SP1 SSBP1 SSBP2 SSBP3 SSBP4 TOLLIP UPF1	10 interacting genes: CDCA3 CSF1R FGFR2 GTF2F1 LDB1 MBP POLR2A PTPN11 SNAI1 TYRO3
Entrez ID		8861	58190
HPRD ID		09144	05615
Ensembl ID		ENSG00000198728	ENSG00000144579
Uniprot IDs		Q86U70	Q9GZU7
PDB IDs		2XJY 2XJZ 2YPA	1T9Z 1TA0 2GHQ 2GHT 3L0B 3L0C 3L0Y 3PGL 4YGY 4YH1 6DU3
Enriched GO Terms of Interacting Partners?
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