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KAT2B and ING1
Number of citations of the paper that reports this interaction (PubMedID
12015309
)
32
Data Source:
HPRD
(in vivo)
KAT2B
ING1
Description
lysine acetyltransferase 2B
inhibitor of growth family member 1
Image
GO Annotations
Cellular Component
PCAF Complex
Kinetochore
Nucleus
Nucleoplasm
Ada2/Gcn5/Ada3 Transcription Activator Complex
Centrosome
A Band
I Band
Protein-containing Complex
Actomyosin
Nucleus
Molecular Function
RNA Polymerase II Regulatory Region Sequence-specific DNA Binding
Chromatin Binding
Transcription Coregulator Activity
Transcription Coactivator Activity
Diamine N-acetyltransferase Activity
Histone Acetyltransferase Activity
Lysine N-acetyltransferase Activity, Acting On Acetyl Phosphate As Donor
Cyclin-dependent Protein Serine/threonine Kinase Inhibitor Activity
Protein Binding
Transcription Factor Binding
Acetyltransferase Activity
Protein Kinase Binding
Histone Deacetylase Binding
Peptide-lysine-N-acetyltransferase Activity
Protein Binding
Methylated Histone Binding
Metal Ion Binding
Biological Process
Chromatin Remodeling
Transcription Initiation From RNA Polymerase II Promoter
Protein Acetylation
Cell Cycle Arrest
Notch Signaling Pathway
Positive Regulation Of Transcription Of Notch Receptor Target
Heart Development
Negative Regulation Of Cell Proliferation
Regulation Of Protein ADP-ribosylation
Viral Process
Protein Deubiquitination
N-terminal Peptidyl-lysine Acetylation
Internal Peptidyl-lysine Acetylation
Peptidyl-lysine Acetylation
Cellular Response To Insulin Stimulus
Histone H3 Acetylation
Histone H3-K9 Acetylation
Regulation Of Megakaryocyte Differentiation
Positive Regulation Of Gluconeogenesis
Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity
Positive Regulation Of Notch Signaling Pathway
Positive Regulation Of Gene Expression, Epigenetic
Positive Regulation Of Transcription By RNA Polymerase II
Negative Regulation Of Centriole Replication
Rhythmic Process
Limb Development
Negative Regulation Of RRNA Processing
Cell Cycle
Negative Regulation Of Cell Proliferation
Regulation Of Cell Death
Negative Regulation Of Cell Growth
Positive Regulation Of Transcription, DNA-templated
Pathways
Pre-NOTCH Transcription and Translation
Pre-NOTCH Transcription and Translation
YAP1- and WWTR1 (TAZ)-stimulated gene expression
Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells
NOTCH1 Intracellular Domain Regulates Transcription
NOTCH1 Intracellular Domain Regulates Transcription
Constitutive Signaling by NOTCH1 PEST Domain Mutants
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants
HATs acetylate histones
Notch-HLH transcription pathway
B-WICH complex positively regulates rRNA expression
Physiological factors
Metalloprotease DUBs
RNA Polymerase I Transcription Initiation
RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function
RUNX3 regulates NOTCH signaling
RUNX3 regulates NOTCH signaling
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH3 Intracellular Domain Regulates Transcription
NOTCH4 Intracellular Domain Regulates Transcription
Estrogen-dependent gene expression
Regulation of FOXO transcriptional activity by acetylation
Drugs
Coenzyme A
(3E)-4-(1-METHYL-1H-INDOL-3-YL)BUT-3-EN-2-ONE
N-(3-AMINOPROPYL)-2-NITROBENZENAMINE
Diseases
GWAS
Drug abuse (
26202629
)
Mean arterial pressure (alcohol consumption interaction) (
24376456
)
Mean corpuscular hemoglobin (
27863252
)
Mean corpuscular volume (
29403010
27863252
)
Optic disc size (
31809533
)
Post-traumatic stress disorder (
24677629
)
Staphylococcus aureus nasal carriage (intermittent) (
26569114
)
Systolic blood pressure (
30224653
30578418
)
Blood protein levels (
30072576
)
Erosive tooth wear (severe vs non-severe) (
29898447
)
Interacting Genes
121 interacting genes:
ACTN1
ACTN2
AKT1
AR
ARHGDIA
ARNTL
ATF4
ATXN3
BRCA2
CCNA2
CCND1
CCNT1
CDC25B
CDCA4
CDK2
CDKN1B
CDT1
CEBPB
CEP250
CIITA
CLOCK
CREBBP
CTBP1
CTNNB1
CUX1
DACH2
DEK
EP300
ESRRA
ETV1
EZH2
GATAD2A
GATAD2B
H1-1
H1-5
H2AC20
H2AC4
H2BC21
H2BC3
H3-3A
H3-4
H3C1
H3C14
H4-16
H4C1
HIPK2
HMGA1
HMGN2
HNF1A
HNRNPU
HOXB9
HSD11B2
HTT
ING1
IRF1
IRF2
IRF7
JDP2
KLF10
KLF13
KLF2
LIN28B
MAPK14
MAPRE1
MDM2
MECOM
MYC
MYOD1
NCOA1
NCOA3
NCOA4
NFATC1
NFE2
NFE4
NOTCH1
NOTCH3
NPAS2
NR1H3
NR4A1
NRIP1
ONECUT1
PARP1
PDK1
PGR
PLAGL1
PNMA1
POLR2A
PTF1A
RAB11A
RARA
RB1
RBM8A
RBPJ
RELA
RPS6KB1
RPS6KB2
SAT2
SATB1
SERBP1
SERTAD1
SERTAD2
SIRT2
SMAD1
SMAD2
SMAD3
SRCAP
TACC2
TAL1
TCF3
TMF1
TP53
TP63
TP73
TRIM14
TTF1
TWIST1
UBE2D1
UBE2D2
UBE2D3
XRCC6
YY1
28 interacting genes:
BRMS1
BRMS1L
COPS2
CYTOR
DMAP1
EP300
ESR1
H3C14
HDAC1
HDAC2
KAT2B
MRGBP
NQO1
PCNA
RBBP4
RBBP7
RBP1
SAP30
SFN
SIN3A
TP53
UBC
YWHAB
YWHAE
YWHAG
YWHAH
YWHAQ
YWHAZ
Entrez ID
8850
3621
HPRD ID
06780
03337
Ensembl ID
ENSG00000114166
ENSG00000153487
Uniprot IDs
Q92831
A0A0C4DFW2
Q9UK53
PDB IDs
1CM0
1JM4
1N72
1WUG
1WUM
1ZS5
2RNW
2RNX
3GG3
4NSQ
5FDZ
5FE0
5FE1
5FE2
5FE3
5FE4
5FE5
5FE6
5FE7
5FE8
5FE9
5LVQ
5LVR
5MKX
6J3O
2QIC
Enriched GO Terms of Interacting Partners
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