CCK and ENPEP

Number of citations of the paper that reports this interaction (PubMedID 8804068)
14

Data Source:
HPRD (in vivo, in vitro)

		CCK	ENPEP
Description		cholecystokinin	glutamyl aminopeptidase
Image		No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Axon Dendrite Axon Initial Segment Terminal Bouton Axon Hillock Perikaryon	Cytoplasm Lysosomal Membrane Plasma Membrane Integral Component Of Plasma Membrane Brush Border External Side Of Plasma Membrane Apical Plasma Membrane Cytoplasmic Vesicle Apical Part Of Cell Extracellular Exosome
	Molecular Function	Hormone Activity Neuropeptide Hormone Activity Peptide Hormone Receptor Binding	Aminopeptidase Activity Zinc Ion Binding Peptide Binding Metalloaminopeptidase Activity
	Biological Process	Neuron Migration Release Of Cytochrome C From Mitochondria Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction G Protein-coupled Receptor Signaling Pathway Protein Kinase C-activating G Protein-coupled Receptor Signaling Pathway Axonogenesis Digestion Memory Positive Regulation Of Cell Proliferation Visual Learning Positive Regulation Of Glutamate Secretion Positive Regulation Of Protein Complex Assembly Negative Regulation Of Appetite Eating Behavior Positive Regulation Of Peptidyl-tyrosine Phosphorylation Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Eating Behavior Positive Regulation Of Sensory Perception Of Pain Negative Regulation Of Behavioral Fear Response Positive Regulation Of Behavioral Fear Response	Angiogenesis Angiotensin Maturation Regulation Of Systemic Arterial Blood Pressure By Renin-angiotensin Proteolysis Cell-cell Signaling Cell Proliferation Cell Migration Glomerulus Development Peptide Catabolic Process
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events	Metabolism of Angiotensinogen to Angiotensins
Drugs			Glutamic Acid
Diseases
GWAS		Body mass index ( 24348519 28892062 28448500) Body mass index (joint analysis main effects and physical activity interaction) ( 28448500) Body mass index (SNP x SNP interaction) ( 22344221) Night sleep phenotypes ( 27126917)	Atrial fibrillation/atrial flutter ( 17603472) Blood pressure ( 21572416) Cognitive decline rate in late mild cognitive impairment ( 26252872) Hypertension ( 30487518) Iris color (a* coordinate) ( 29109912) Iris color (b* coordinate) ( 29109912) Iris heterochromicity ( 29109912) Lung cancer ( 28604730) Mean arterial pressure ( 30487518) Medication use (agents acting on the renin-angiotensin system) ( 31015401) Medication use (calcium channel blockers) ( 31015401) Medication use (diuretics) ( 31015401) Metabolic traits ( 21886157) Pursuit maintenance gain ( 29064472) Systolic blood pressure ( 28135244 30487518 30578418)
Interacting Genes		6 interacting genes: CCKAR CCKBR CPE ENPEP MEP1A MEP1B	2 interacting genes: AGT CCK
Entrez ID		885	2028
HPRD ID		00321	08848
Ensembl ID		ENSG00000187094	ENSG00000138792
Uniprot IDs		P06307 Q6FG82	Q07075
PDB IDs			4KX7 4KX8 4KX9 4KXA 4KXB 4KXC 4KXD
Enriched GO Terms of Interacting Partners?
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?