IL18RAP and CD48

Number of citations of the paper that reports this interaction (PubMedID 15760905)
8

Data Source:
HPRD (in vivo)

		IL18RAP	CD48
Description		interleukin 18 receptor accessory protein	CD48 molecule
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GO Annotations	Cellular Component	Plasma Membrane Interleukin-18 Receptor Complex	Plasma Membrane Membrane Anchored Component Of Membrane Intrinsic Component Of Plasma Membrane Membrane Raft Extracellular Exosome
	Molecular Function	Interleukin-18 Receptor Activity NAD(P)+ Nucleosidase Activity NAD+ Nucleotidase, Cyclic ADP-ribose Generating	Antigen Binding Protein Binding Signaling Receptor Activity
	Biological Process	Inflammatory Response Immune Response Cell Proliferation Interferon-gamma Production Interleukin-6 Production Interleukin-18-mediated Signaling Pathway T-helper 1 Cell Cytokine Production Neutrophil Activation Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of NF-kappaB Transcription Factor Activity Cellular Response To Hydrogen Peroxide	Regulation Of Adaptive Immune Response Defense Response Leukocyte Migration
Pathways		Interleukin-18 signaling	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29785011) Allergic sensitization ( 23817571) Asthma ( 31619474) Asthma or allergic disease (pleiotropy) ( 29785011) Atopic dermatitis ( 23042114 26482879) Blood protein levels ( 30072576 28240269) Celiac disease ( 22057235 20190752 18311140) Crohn's disease ( 28067908 21102463) Delirium ( 29631748) Inflammatory bowel disease ( 28067908 23128233) Leprosy ( 25642632) Liver fibrosis in pediatric non-alcoholic fatty acid liver disease ( 28918882) Lymphocyte percentage of white cells ( 27863252) Primary biliary cholangitis ( 26394269) Serum protein levels (sST2) ( 23999434) Systemic lupus erythematosus ( 28714469)	Blood protein levels ( 30072576 29875488) Inflammatory bowel disease ( 23128233) Itch intensity from mosquito bite ( 28199695) Multiple sclerosis ( 31604244) Venous thromboembolism adjusted for sickle cell variant rs77121243-T ( 28203683)
Interacting Genes		3 interacting genes: APP CD48 IL18	10 interacting genes: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		8807	962
HPRD ID		05147	00177
Ensembl ID		ENSG00000115607	ENSG00000117091
Uniprot IDs		O95256	A0A087X1S7 P09326
PDB IDs		3WO4	2EDO
Enriched GO Terms of Interacting Partners?
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