SUCLG1 and SUCLG2

Number of citations of the paper that reports this interaction (PubMedID 10873456)
20

Data Source:
HPRD (in vitro)

		SUCLG1	SUCLG2
Description		succinate-CoA ligase GDP/ADP-forming subunit alpha	succinate-CoA ligase GDP-forming subunit beta
Image			No pdb structure
GO Annotations	Cellular Component	Mitochondrion Mitochondrial Matrix Cytosol Plasma Membrane	Mitochondrion Mitochondrial Matrix Plasma Membrane Succinate-CoA Ligase Complex Succinate-CoA Ligase Complex (GDP-forming)
	Molecular Function	Nucleotide Binding RNA Binding Nucleoside Diphosphate Kinase Activity Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Cofactor Binding	Magnesium Ion Binding Succinate-CoA Ligase (ADP-forming) Activity Succinate-CoA Ligase (GDP-forming) Activity Protein Binding ATP Binding GTP Binding GDP Binding Protein-containing Complex Binding
	Biological Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process Nucleoside Diphosphate Phosphorylation Nucleoside Triphosphate Biosynthetic Process	Tricarboxylic Acid Cycle Succinyl-CoA Metabolic Process Succinate Metabolic Process
Pathways		Citric acid cycle (TCA cycle)	Citric acid cycle (TCA cycle)
Drugs		Succinic acid	Succinic acid Phenethyl Isothiocyanate
Diseases		Mitochondrial DNA depletion syndrome (MDS)
GWAS		Coronary artery calcification ( 23870195) Gut microbiota (functional units) ( 27694959)	Blood metabolite levels ( 24816252) Body mass index ( 28552196) Cerebrospinal AB1-42 levels in Alzheimer's disease dementia ( 25027320) Corneal astigmatism ( 22144915) Diabetic kidney disease ( 26305897) FEV1 ( 30804560) Height ( 20881960) Hip circumference ( 28552196) IgE levels ( 23146381) Lung function (FVC) ( 28166213 30804560) Metabolite levels ( 23823483) Spontaneous preterm birth with premature rupture of membranes ( 31194736) Thrombin-activatable fibrinolysis inhibitor activation peptide ( 29378355) Urinary metabolite levels in chronic kidney disease ( 31959995)
Interacting Genes		2 interacting genes: CHMP1B SUCLG2	2 interacting genes: GPR143 SUCLG1
Entrez ID		8802	8801
HPRD ID		18128	06799
Ensembl ID		ENSG00000163541	ENSG00000172340
Uniprot IDs		P53597	Q96I99
PDB IDs		6G4Q
Enriched GO Terms of Interacting Partners?
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