TNFRSF10A and TNFRSF10D

Number of citations of the paper that reports this interaction (PubMedID 16319225)
70

Data Source:
HPRD (in vivo, in vitro)

		TNFRSF10A	TNFRSF10D
Description		TNF receptor superfamily member 10a	TNF receptor superfamily member 10d
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Integral Component Of Membrane	Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Protease Binding Death Receptor Activity Protein Binding Transcription Factor Binding Signaling Receptor Activity TRAIL Binding	Transmembrane Signaling Receptor Activity TRAIL Binding
	Biological Process	Apoptotic Process Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Activation Of NF-kappaB-inducing Kinase Activity Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors TRAIL-activated Apoptotic Signaling Pathway Regulation Of Apoptotic Process Positive Regulation Of Apoptotic Process Leukocyte Migration Cellular Response To Mechanical Stimulus Extrinsic Apoptotic Signaling Pathway Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Via Death Domain Receptors	Apoptotic Process Signal Transduction Cell Surface Receptor Signaling Pathway Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Leukocyte Migration
Pathways		Caspase activation via Death Receptors in the presence of ligand Cell surface interactions at the vascular wall Regulation by c-FLIP RIPK1-mediated regulated necrosis CASP8 activity is inhibited TP53 Regulates Transcription of Death Receptors and Ligands Dimerization of procaspase-8 TRAIL signaling	Cell surface interactions at the vascular wall TP53 Regulates Transcription of Death Receptors and Ligands TRAIL signaling
Drugs
Diseases
GWAS		Advanced age-related macular degeneration ( 26691988) Age-related macular degeneration ( 21909106 23455636) Attention deficit hyperactivity disorder ( 20732625) Central serous retinopathy ( 31872073)	Attention deficit hyperactivity disorder ( 20732625)
Interacting Genes		15 interacting genes: BCL10 BTK CASP8 CD4 COL2A1 DAP3 FADD MADD MOAP1 RASSF1 RIPK1 TNFRSF10B TNFRSF10D TNFSF10 TRADD	3 interacting genes: TNFRSF10A TNFRSF10B TNFSF10
Entrez ID		8797	8793
HPRD ID		04679	04682
Ensembl ID		ENSG00000104689	ENSG00000173530
Uniprot IDs		O00220	Q9UBN6
PDB IDs		5CIR
Enriched GO Terms of Interacting Partners?
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