MYOM1 and TTN

Number of citations of the paper that reports this interaction (PubMedID 7588733)
10

Data Source:
HPRD (in vitro)

		MYOM1	TTN
Description		myomesin 1	titin
Image
GO Annotations	Cellular Component	Striated Muscle Myosin Thick Filament Striated Muscle Thin Filament Sarcomere Z Disc M Band	Condensed Nuclear Chromosome Extracellular Region Cytosol Striated Muscle Thin Filament Sarcomere Z Disc M Band I Band Extracellular Exosome
	Molecular Function	Protein Binding Structural Constituent Of Muscle Kinase Binding Identical Protein Binding Protein Homodimerization Activity Actin Filament Binding Muscle Alpha-actinin Binding	Protease Binding Protein Serine/threonine Kinase Activity Protein Tyrosine Kinase Activity Calcium Ion Binding Protein Binding Calmodulin Binding ATP Binding Structural Constituent Of Muscle Enzyme Binding Protein Kinase Binding Telethonin Binding Identical Protein Binding Actinin Binding Protein Self-association Actin Filament Binding Muscle Alpha-actinin Binding Structural Molecule Activity Conferring Elasticity
	Biological Process	Extraocular Skeletal Muscle Development Muscle Contraction Striated Muscle Contraction Actin Filament Organization Positive Regulation Of Gene Expression Protein Kinase A Signaling Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Sarcomere Organization Cardiac Muscle Fiber Development Positive Regulation Of Protein Secretion Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Striated Muscle Myosin Thick Filament Assembly	Platelet Degranulation Cardiac Muscle Hypertrophy Muscle Contraction Striated Muscle Contraction Actin Filament Organization Mitotic Chromosome Condensation Positive Regulation Of Gene Expression Protein Kinase A Signaling Peptidyl-tyrosine Phosphorylation Muscle Filament Sliding Skeletal Muscle Thin Filament Assembly Skeletal Muscle Myosin Thick Filament Assembly Detection Of Muscle Stretch Sarcomere Organization Regulation Of Protein Kinase Activity Cardiac Muscle Fiber Development Sarcomerogenesis Positive Regulation Of Protein Secretion Regulation Of Catalytic Activity Response To Calcium Ion Cardiac Myofibril Assembly Cardiac Muscle Tissue Morphogenesis Cardiac Muscle Contraction Striated Muscle Myosin Thick Filament Assembly
Pathways			Platelet degranulation Striated Muscle Contraction
Drugs
Diseases			Distal muscular dystrophies, including: Welander distal myopathy (WDM); Tibial muscular dystrophy (TMD); Nonaka distal myopathy with rimmed vacuoles (DMRV); Miyoshi myopathy (MM); Laing myopathy (MPD1); Distal nebulin myopathy (DNM); Distal desminopathy (MFM1); alpha-B Crystallinopathy (MFM2); Distal myotilinopathy (MFM3); Distal zaspopathy (MFM4); Distal myopathy 3 (MPD2, VCPDM) Hypertrophic cardiomyopathy (HCM) Dilated cardiomyopathy (DCM)
GWAS		Brain volume in infants (white matter) ( 28763065) Night sleep phenotypes ( 27126917) Urinary albumin-to-creatinine ratio in non-diabetics ( 26631737)	Atrial fibrillation ( 29290336 30061737 29892015) Bone mineral density (hip) ( 30172743) Breast size ( 22747683) Epstein-Barr virus copy number in lymphoblastoid cell lines ( 28654678) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) PR interval ( 30046033) QT interval ( 20031603 29213071 24952745) Rapid functional decline in sporadic amyotrophic lateral sclerosis ( 26746183) Resting heart rate ( 27798624) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971)
Interacting Genes		3 interacting genes: CLK1 MYH9 TTN	31 interacting genes: ACTA1 ACTN1 ACTN2 ANK1 ANKRD1 ANKRD2 ANKRD23 CALM1 CAPN3 CRYAB FHL1 FHL2 FLNA HSPB2 MAPK1 MYBPC1 MYBPC3 MYH9 MYOM1 MYOM2 MYPN NBR1 NEB OBSCN SQSTM1 SRPK2 TCAP TRIM55 TRIM63 TSC22D2 VAV2
Entrez ID		8736	7273
HPRD ID		04618	01787
Ensembl ID		ENSG00000101605	ENSG00000155657
Uniprot IDs		P52179	A0A0A0MRA3 A0A0A0MTS7 Q7Z3B7 Q8WZ42
PDB IDs		2R15 2Y23 2Y25 3RBS 5FM4 5FM5 5FM8	1BPV 1G1C 1NCT 1NCU 1TIT 1TIU 1TKI 1TNM 1TNN 1WAA 1YA5 2A38 2BK8 2F8V 2ILL 2J8H 2J8O 2NZI 2RQ8 2WP3 2WWK 2WWM 2Y9R 3B43 3KNB 3LCY 3LPW 3PUC 3Q5O 3QP3 4C4K 4JNW 4O00 4QEG 4UOW 5BS0 5JDD 5JDE 5JDJ 5JOE 6DL4 6H4L 6HCI 6I0Y 6SDB
Enriched GO Terms of Interacting Partners?
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