GPAA1 and PIGU

Number of citations of the paper that reports this interaction (PubMedID 22939629)
262

Data Source:
BioGRID (biochemical)
HPRD (in vivo)

		GPAA1	PIGU
Description		glycosylphosphatidylinositol anchor attachment 1	phosphatidylinositol glycan anchor biosynthesis class U
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Membrane GPI-anchor Transamidase Complex	Endoplasmic Reticulum Membrane Plasma Membrane Membrane Integral Component Of Endoplasmic Reticulum Membrane GPI-anchor Transamidase Complex
	Molecular Function	GPI-anchor Transamidase Activity Protein Binding Tubulin Binding GPI Anchor Binding	GPI-anchor Transamidase Activity GPI Anchor Binding
	Biological Process	Protein Retention In ER Lumen Attachment Of GPI Anchor To Protein Protein-containing Complex Assembly	GPI Anchor Biosynthetic Process Attachment Of GPI Anchor To Protein Protein Localization To Cell Surface Regulation Of JAK-STAT Cascade
Pathways		Attachment of GPI anchor to uPAR	Attachment of GPI anchor to uPAR
Drugs
Diseases
GWAS		Bipolar disorder ( 31043756) Bipolar I disorder ( 31043756) Serum metabolite levels ( 23093944)	Bipolar disorder ( 31043756) Brown vs. black hair color ( 30531825) Colorectal cancer or advanced adenoma ( 30510241) Estimated glomerular filtration rate ( 31152163) Lipid traits (pleiotropy) (HIPO component 1) ( 30289880) Melanoma ( 28212542) Smoking status (ever vs never smokers) ( 30643258) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex interaction ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971) Weight ( 28552196)
Interacting Genes		17 interacting genes: ADAMDEC1 AQP2 CACNG8 DGAT1 EIF3E GIT1 GRIK5 LRRC14 LY6E NDRG1 PIGK PIGT PIGU PIN1 PRR13 TERF2IP TONSL	1 interacting genes: GPAA1
Entrez ID		8733	128869
HPRD ID		04334	12250
Ensembl ID		ENSG00000197858	ENSG00000101464
Uniprot IDs		O43292	Q9H490
PDB IDs
Enriched GO Terms of Interacting Partners?
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