SERPINH1 and KLF13

Number of citations of the paper that reports this interaction (PubMedID 11748222)
29

Data Source:
HPRD (in vitro, in vivo)

		SERPINH1	KLF13
Description		serpin family H member 1	Kruppel like factor 13
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Space Endoplasmic Reticulum Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Raft Collagen-containing Extracellular Matrix	Nuclear Chromatin Nucleus
	Molecular Function	RNA Binding Serine-type Endopeptidase Inhibitor Activity Collagen Binding Unfolded Protein Binding	RNA Polymerase II Proximal Promoter Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Protein Binding Metal Ion Binding
	Biological Process	Chondrocyte Development Involved In Endochondral Bone Morphogenesis Response To Unfolded Protein Negative Regulation Of Endopeptidase Activity Collagen Fibril Organization Collagen Biosynthetic Process Protein Maturation	Regulation Of Transcription By RNA Polymerase II Transcription By RNA Polymerase II Negative Regulation Of Cell Proliferation Negative Regulation Of Erythrocyte Differentiation Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Collagen biosynthesis and modifying enzymes
Drugs
Diseases
GWAS		Coronary artery disease ( 29212778) Height ( 28552196 20881960 22021425 25282103 25429064 31562340 28270201) Hip circumference adjusted for BMI ( 25673412) Waist circumference adjusted for BMI (joint analysis main effects and physical activity interaction) ( 28448500) Waist circumference adjusted for BMI in active individuals ( 28448500) Waist circumference adjusted for body mass index ( 28448500)	Brain volume in infants (intracranial brain volume) ( 28763065) Eosinophilic esophagitis ( 25017104) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Psoriasis ( 28537254) Waist-to-hip ratio adjusted for BMI (adjusted for smoking behaviour) ( 28443625) Waist-to-hip ratio adjusted for BMI (joint analysis for main effect and physical activity interaction) ( 28448500) Waist-to-hip ratio adjusted for BMI (joint analysis main effects and smoking interaction) ( 28443625) Waist-to-hip ratio adjusted for BMI in active individuals ( 28448500) Waist-to-hip ratio adjusted for BMI in non-smokers ( 28443625) Waist-to-hip ratio adjusted for body mass index ( 25673412 28448500)
Interacting Genes		17 interacting genes: BAG6 BRCA2 C1QL3 CD9 CDK9 CEP70 COL26A1 ESR2 FEZ1 H1-5 KLF13 NSG2 PPARG SLC2A4 SLC35F6 UBQLN4 UBTF	9 interacting genes: CREBBP EP300 KAT2B PCBD1 PRPF4B SERPINH1 SIN3A SREBF1 SREBF2
Entrez ID		871	51621
HPRD ID		02968	05620
Ensembl ID		ENSG00000149257	ENSG00000169926
Uniprot IDs		A0A024R5K8 A8K259 P50454	Q9Y2Y9 X5DNR2
PDB IDs
Enriched GO Terms of Interacting Partners?
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