EIF3D and EIF3J

Number of citations of the paper that reports this interaction (PubMedID 22190034)
277

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		EIF3D	EIF3J
Description		eukaryotic translation initiation factor 3 subunit D	eukaryotic translation initiation factor 3 subunit J
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Membrane Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Eukaryotic Translation Initiation Factor 3 Complex, EIF3m	Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex
	Molecular Function	RNA Binding Translation Initiation Factor Activity Protein Binding MRNA Cap Binding	Translation Initiation Factor Activity Protein Binding
	Biological Process	Formation Of Cytoplasmic Translation Initiation Complex Cap-dependent Translational Initiation Translational Initiation Positive Regulation Of Translation IRES-dependent Viral Translational Initiation Viral Translational Termination-reinitiation Positive Regulation Of MRNA Binding	Formation Of Cytoplasmic Translation Initiation Complex Translational Initiation
Pathways		L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS			Anti-Toxoplasma gondii IgG seropositivity ( 30610941)
Interacting Genes		13 interacting genes: BEND5 CREBBP DNAJB11 EIF3G EIF3J EIF3L EIF5 HOMER3 LZTS2 PHLDA1 REL SAT1 TRIM27	14 interacting genes: CASP3 CSNK2A1 EIF3A EIF3B EIF3C EIF3D EIF3K GNB5 GOLM1 MAGED1 METTL3 SIAH1 TADA3 TPD52L1
Entrez ID		8664	8669
HPRD ID		04888	04883
Ensembl ID		ENSG00000100353	ENSG00000104131
Uniprot IDs		O15371	A0A024R5S5 O75822
PDB IDs			2KRB 3BPJ
Enriched GO Terms of Interacting Partners?
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