LAMTOR3 and CPNE6

Number of citations of the paper that reports this interaction (PubMedID 21900206)
114

Data Source:
BioGRID (two hybrid)

		LAMTOR3	CPNE6
Description		late endosomal/lysosomal adaptor, MAPK and MTOR activator 3	copine 6
Image			No pdb structure
GO Annotations	Cellular Component	Lysosomal Membrane Plasma Membrane Focal Adhesion Endosome Membrane Specific Granule Membrane Extracellular Exosome Tertiary Granule Membrane Ragulator Complex	Endosome Plasma Membrane Membrane Axon Dendrite Perikaryon Synapse Clathrin-coated Endocytic Vesicle Extracellular Exosome
	Molecular Function	Guanyl-nucleotide Exchange Factor Activity Protein Binding Kinase Activator Activity Molecular Adaptor Activity	Phosphatidylserine Binding Transporter Activity Calcium Ion Binding Protein Binding Calcium-dependent Phospholipid Binding
	Biological Process	MAPK Cascade Activation Of MAPKK Activity Cell Cycle Arrest Regulation Of Macroautophagy Positive Regulation Of TOR Signaling Cellular Protein Localization Neutrophil Degranulation Cellular Response To Amino Acid Stimulus	Lipid Metabolic Process Chemical Synaptic Transmission Nervous System Development Vesicle-mediated Transport Glycerophospholipid Biosynthetic Process Cellular Response To Calcium Ion Positive Regulation Of Dendrite Extension
Pathways		Macroautophagy mTOR signalling mTORC1-mediated signalling Energy dependent regulation of mTOR by LKB1-AMPK TP53 Regulates Metabolic Genes MAP2K and MAPK activation Neutrophil degranulation Regulation of PTEN gene transcription Amino acids regulate mTORC1	Glycerophospholipid biosynthesis
Drugs
Diseases
GWAS
Interacting Genes		17 interacting genes: ADAMTS10 BHMT CDKN2A CEBPZ CPNE6 IBTK LAMTOR2 MAP2K1 MAP2K2 MAPK1 MAPK3 MBD2 NIF3L1 PDE4DIP QARS1 SUFU UBR1	13 interacting genes: AK5 ANXA7 CDKN1A GRB7 LAMTOR3 MAPK11 MEOX2 NOTCH3 OS9 PIN1 SMN1 TK1 TTR
Entrez ID		8649	9362
HPRD ID		04485	05748
Ensembl ID		ENSG00000109270	ENSG00000100884
Uniprot IDs		Q9UHA4	B3KWK1 O95741
PDB IDs		1SKO 2ZL1 3CPT 5X6U 5X6V 5Y39 5Y3A 6B9X 6EHP 6EHR 6NZD 6U62 6ULG
Enriched GO Terms of Interacting Partners?
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