USO1 and GBF1

Number of citations of the paper that reports this interaction (PubMedID 12634853)
32

Data Source:
BioGRID (proximity labelling technology)
HPRD (two hybrid, in vivo, in vitro)

		USO1	GBF1
Description		USO1 vesicle transport factor	golgi brefeldin A resistant guanine nucleotide exchange factor 1
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Fibrillar Center Endoplasmic Reticulum Golgi Apparatus Golgi Stack Cytosol ER To Golgi Transport Vesicle Membrane Membrane Transport Vesicle Perinuclear Region Of Cytoplasm	Golgi Membrane Mitochondrion Peroxisome Endoplasmic Reticulum Lumen Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Golgi Stack Cis-Golgi Network Trans-Golgi Network Lipid Droplet Cytosol Membrane Cell Leading Edge
	Molecular Function	RNA Binding Protein Binding Cadherin Binding	Guanyl-nucleotide Exchange Factor Activity ARF Guanyl-nucleotide Exchange Factor Activity Protein Binding Phosphatidylinositol-3,4,5-trisphosphate Binding Phosphatidylinositol-3,5-bisphosphate Binding
	Biological Process	Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Golgi Organization Small GTPase Mediated Signal Transduction Secretory Granule Localization Transcytosis COPII Vesicle Coating Golgi Vesicle Docking Vesicle Fusion With Golgi Apparatus Membrane Fusion Regulation Of Cellular Response To Insulin Stimulus	Cell Activation Involved In Immune Response ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Post-Golgi Vesicle-mediated Transport Golgi To Endosome Transport Golgi Organization Regulation Of Mitotic Cell Cycle Protein Transport Viral Process Neutrophil Chemotaxis Regulation Of ARF Protein Signal Transduction Protein Localization To Golgi Apparatus Retrograde Transport, Endosome To Golgi COPI Coating Of Golgi Vesicle Establishment Of Monopolar Cell Polarity Protein Localization To Endoplasmic Reticulum Exit Site Golgi Disassembly Endoplasmic Reticulum-Golgi Intermediate Compartment Organization Cellular Response To Virus Reactive Oxygen Species Biosynthetic Process Protein Localization To Endoplasmic Reticulum Tubular Network Regulation Of Protein Localization To Cell Surface
Pathways		Golgi Cisternae Pericentriolar Stack Reorganization COPII-mediated vesicle transport COPI-mediated anterograde transport	trans-Golgi Network Vesicle Budding VxPx cargo-targeting to cilium COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Response to (pegylated) interferon in HBeAg-negative hepatitis B ( 30715261) Subjective response to lithium treatment in bipolar disorder ( 26503763)	General cognitive ability ( 29844566) Hand grip strength ( 29313844) Household income (MTAG) ( 31844048) Intelligence (MTAG) ( 29326435) Parkinson's disease or first degree relation to individual with Parkinson's disease ( 31701892) QT interval ( 24952745) Smoking initiation (ever regular vs never regular) ( 30679032) Waist-to-hip ratio adjusted for BMI ( 26426971) Waist-to-hip ratio adjusted for BMI (age >50) ( 26426971) Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test) ( 26426971)
Interacting Genes		25 interacting genes: AKAP9 BET1L C1orf94 CASP3 CASP8 CSNK2B DUSP12 EEA1 G3BP2 GABPB1 GAK GBF1 GOLGA2 GOLGB1 GOSR1 GOSR2 NSF PHYKPL PLCG1 RAB1A SCFD1 STX5 STXBP1 XPO7 YKT6	6 interacting genes: CDK1 PNPLA2 SRPK2 UBC USO1 YWHAG
Entrez ID		8615	8729
HPRD ID		09135	04740
Ensembl ID		ENSG00000138768	ENSG00000107862
Uniprot IDs		O60763	Q92538
PDB IDs		2W3C
Enriched GO Terms of Interacting Partners?
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