ALG10 and KCNH1

Number of citations of the paper that reports this interaction (PubMedID 9722534)
11

Data Source:
HPRD (in vitro)

		ALG10	KCNH1
Description		ALG10 alpha-1,2-glucosyltransferase	potassium voltage-gated channel subfamily H member 1
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Membrane Integral Component Of Membrane	Nuclear Inner Membrane Plasma Membrane Integral Component Of Plasma Membrane Voltage-gated Potassium Channel Complex Cell Surface Cell Junction Dendrite Axolemma Early Endosome Membrane Perikaryon Intracellular Membrane-bounded Organelle Perinuclear Region Of Cytoplasm Postsynaptic Density Membrane Integral Component Of Presynaptic Membrane
	Molecular Function	Dolichyl-phosphate-glucose-glycolipid Alpha-glucosyltransferase Activity Dolichyl Pyrophosphate Glc2Man9GlcNAc2 Alpha-1,2-glucosyltransferase Activity	Voltage-gated Potassium Channel Activity Delayed Rectifier Potassium Channel Activity Protein Binding Calmodulin Binding Protein Kinase Binding Cyclic Nucleotide Binding Identical Protein Binding Ion Channel Binding Protein-containing Complex Binding 14-3-3 Protein Binding Phosphatidylinositol Bisphosphate Binding
	Biological Process	Dolichol-linked Oligosaccharide Biosynthetic Process	Startle Response Potassium Ion Transport Myoblast Fusion Regulation Of Ion Transmembrane Transport Regulation Of Cell Proliferation Regulation Of Membrane Potential Phosphatidylinositol-mediated Signaling Cellular Response To Calcium Ion Potassium Ion Transmembrane Transport
Pathways		Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein	Voltage gated Potassium channels
Drugs			Imipramine Astemizole
Diseases
GWAS		Chronotype ( 30696823) Heart rate increase in response to exercise ( 29497042) Heart rate response to recovery post exercise ( 29769521) Heart rate response to recovery post exercise (10 sec) ( 29497042) Heart rate response to recovery post exercise (20 sec) ( 29497042) Heart rate response to recovery post exercise (30 sec) ( 29497042) Heart rate response to recovery post exercise (40 sec) ( 29497042) Heart rate response to recovery post exercise (50 sec) ( 29497042) Methadone dose in opioid dependence ( 28115739) Morning person ( 30696823)	Blond vs. brown/black hair color ( 30531825) Bone mineral density (femoral neck) ( 27424934) Bone mineral density (spine) and age at menarche ( 26312577) Bone mineral density (total hip) ( 27424934) Cancer ( 27197191) Circulating vasoactive peptide levels ( 23381795) Cobalt levels ( 26025379)
Interacting Genes		2 interacting genes: KCNH1 KCNH2	10 interacting genes: ALG10 CALM1 FASTKD5 KCNB1 KCNC1 KCNF1 KCNH5 MTDH NTAQ1 SDCBP
Entrez ID		84920	3756
HPRD ID		10346	04492
Ensembl ID		ENSG00000139133	ENSG00000143473
Uniprot IDs		Q5BKT4	O95259
PDB IDs			5J7E
Enriched GO Terms of Interacting Partners?
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