RHOXF2 and EFEMP2

Number of citations of the paper that reports this interaction (PubMedID 16189514)
1016

Data Source:
HPRD (two hybrid)

		RHOXF2	EFEMP2
Description		Rhox homeobox family member 2	EGF containing fibulin extracellular matrix protein 2
Image		No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus	Extracellular Region Basement Membrane Collagen-containing Extracellular Matrix Extracellular Exosome Extracellular Vesicle
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Identical Protein Binding	Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Gene Expression	Elastic Fiber Assembly
Pathways			Molecules associated with elastic fibres Molecules associated with elastic fibres
Drugs
Diseases			Cutis laxa, including: Autosomal dominant cutis laxa (ADCL); Autosomal recessive cutis laxa I (ARCL1); Autosomal recessive cutis laxa II (ARCL2); X-linked recessive cutis laxa (XRCL); Wrinkly skin syndrome
GWAS			Acne (severe) ( 24927181) Birth weight ( 31043758)
Interacting Genes		58 interacting genes: ARID5A ARMCX2 ATN1 ATXN1 CCDC33 CCNK CHAC1 CLASRP CLDN7 CRYBA1 DAB1 DAZAP2 DEDD2 DTX2 DVL2 EFEMP2 EWSR1 FBF1 HNRNPLL HOXC13 KRTAP19-5 KRTAP19-7 LASP1 LENG8 LSM4 LZTS2 MAGED1 MED7 MVP NANOG NEU4 PITX1 PLOD3 POLR3D POU2AF1 PSMF1 RADIL RAMAC RBFOX1 RBFOX2 RBM11 RBPMS SERF2 SNAPC1 SUMO1 TENT5B TENT5C TENT5D TLE5 TMCC2 TOLLIP TRIP13 UBE2I UPF1 UTP6 VAC14 VPS25 ZBTB32	52 interacting genes: AMMECR1 APEX2 AQP1 ATN1 ATXN1 ATXN7 BAG6 C5orf24 CACNA1A CATSPER1 CCDC33 CCND3 CCNK COL8A1 CREB5 DGCR6 FAM107A FAM124B FAM74A4 GFI1B GLRX3 HDAC4 HHEX HOXA1 IL16 LCE2D LCE3C LINGO1 MEOX2 NEDD4L NOS3 NUFIP2 PIDD1 PLSCR1 PLSCR4 PRPF31 PTGER3 RBPMS RERE RHOXF2 RHPN1 RIBC2 SGTA SGTB STK16 TCAF1 TP53 UBQLN1 UBQLN4 ZNF263 ZNF426 ZNF638
Entrez ID		84528	30008
HPRD ID		02345	05221
Ensembl ID		ENSG00000131721	ENSG00000172638
Uniprot IDs		Q9BQY4	A0A024R5G1 O95967 Q9H3D5
PDB IDs			2KL7
Enriched GO Terms of Interacting Partners?
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