HOPX and TLX3

Number of citations of the paper that reports this interaction (PubMedID 20211142)
329

		HOPX	TLX3
Description		HOP homeobox	T cell leukemia homeobox 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nuclear Chromatin Nucleus Cytoplasm	Nuclear Chromatin Nucleoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Protein Binding Sequence-specific DNA Binding
	Biological Process	Trophectodermal Cell Differentiation Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Cell Differentiation Chaperone-mediated Protein Complex Assembly	Neuron Migration Regulation Of Respiratory Gaseous Exchange By Neurological System Process Regulation Of Transcription By RNA Polymerase II Central Nervous System Development Respiratory Gaseous Exchange Negative Regulation Of Neuron Differentiation Neuron Fate Specification
Pathways
Drugs
Diseases			Acute lymphoblastic leukemia (ALL) (precursor T lymphoblastic leukemia)
GWAS		Cadmium levels ( 26025379) Systemic sclerosis ( 30247649)
Interacting Genes		8 interacting genes: COMT EPC1 HDAC2 HOXB9 SRF TCF12 TLX3 ZSCAN1	16 interacting genes: DENND4A GTF2A1L H2BC11 HNRNPUL1 HOPX ING4 IRF9 LMO2 MEIS1 PPP1CC PQBP1 SNTA1 SP1 TLE1 TLE2 ZNF41
Entrez ID		84525	30012
HPRD ID		06280	06868
Ensembl ID		ENSG00000171476	ENSG00000164438
Uniprot IDs		Q9BPY8	O43711
PDB IDs
Enriched GO Terms of Interacting Partners?
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