CASQ2 and TRDN

Number of citations of the paper that reports this interaction (PubMedID 9287354)
135

Data Source:
HPRD (in vivo, in vitro)

		CASQ2	TRDN
Description		calsequestrin 2	triadin
Image			No pdb structure
GO Annotations	Cellular Component	Cell Cytoplasm Junctional Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Z Disc Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen Calcium Channel Complex	Cell Endoplasmic Reticulum Cytosol Plasma Membrane Junctional Sarcoplasmic Reticulum Membrane Integral Component Of Membrane Sarcoplasmic Reticulum Junctional Membrane Complex Sarcoplasmic Reticulum Membrane Sarcoplasmic Reticulum Lumen
	Molecular Function	Calcium Ion Binding Protein Binding Protein Homodimerization Activity Calcium-dependent Protein Binding	Signaling Receptor Binding Protein Binding Protein Binding, Bridging Ion Channel Binding
	Biological Process	Regulation Of Heart Rate Detection Of Calcium Ion Striated Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Sarcomere Organization Sequestering Of Calcium Ion Protein Polymerization Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cardiac Muscle Contraction Regulation Of Membrane Repolarization Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Cellular Response To Caffeine Purkinje Myocyte To Ventricular Cardiac Muscle Cell Signaling Negative Regulation Of Potassium Ion Transmembrane Transporter Activity Regulation Of Cardiac Conduction	Cellular Calcium Ion Homeostasis Muscle Contraction Response To Bacterium Regulation Of Cell Communication By Electrical Coupling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Cytoplasmic Microtubule Organization Ion Transmembrane Transport Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Heart Contraction Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Cardiac Muscle Cell Membrane Potential Endoplasmic Reticulum Membrane Organization Positive Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Regulation Of Cardiac Conduction
Pathways		Stimuli-sensing channels Ion homeostasis	Stimuli-sensing channels Ion homeostasis
Drugs		Calcium Citrate Calcium Phosphate
Diseases		Catecholaminergic polymorphic ventricular tachycardia
GWAS		Atrial fibrillation ( 30061737 29892015) Pulse pressure ( 30578418) QRS duration ( 27577874 30012220 27659466)	Asthma exacerbations in inhaled corticosteroid treatment ( 30697902) Borderline personality disorder ( 28632202) Cerebral amyloid deposition in APOEe4 non-carriers (PET imaging) ( 26252872) Intraocular pressure ( 30591961) Metabolite levels ( 23823483) Nickel levels ( 26025379) Night sleep phenotypes ( 27126917) Post bronchodilator FEV1 ( 26634245)
Interacting Genes		5 interacting genes: ANKRD1 CSNK2A1 CSNK2A2 FBXO7 TRDN	7 interacting genes: ASPH CALM1 CASQ1 CASQ2 HRC RYR1 SOCS3
Entrez ID		845	10345
HPRD ID		00256	04474
Ensembl ID		ENSG00000118729	ENSG00000186439
Uniprot IDs		O14958	A0A590UJV0 H9ME53 Q13061 Q8IVK2
PDB IDs		2VAF
Enriched GO Terms of Interacting Partners?
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