L3MBTL3 and OAZ3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		L3MBTL3	OAZ3
Description		L3MBTL histone methyl-lysine binding protein 3	ornithine decarboxylase antizyme 3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleoplasm Nucleolus	Nucleus Nucleoplasm Cytoplasm Cytosol Blood Microparticle
	Molecular Function	Molecular_function DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Identical Protein Binding	Protein Binding Ornithine Decarboxylase Inhibitor Activity
	Biological Process	Chromatin Organization Regulation Of Transcription, DNA-templated Macrophage Differentiation Granulocyte Differentiation Erythrocyte Maturation	Regulation Of Cellular Amino Acid Metabolic Process Polyamine Biosynthetic Process Spermatogenesis Negative Regulation Of Catalytic Activity Positive Regulation Of Protein Catabolic Process Negative Regulation Of Polyamine Transmembrane Transport
Pathways			Regulation of ornithine decarboxylase (ODC)
Drugs			Ornithine
Diseases
GWAS		Birth weight ( 31043758 27680694) Body mass index ( 25673413) Breast cancer ( 29059683 29058716) Breast cancer (estrogen-receptor negative) ( 29058716) C-reactive protein levels ( 30388399) Chronic kidney disease ( 31152163) Estimated glomerular filtration rate ( 31152163) Heel bone mineral density ( 30598549 28869591) Height ( 28552196 20881960 25282103 25429064 23563607 31562340 18391951) Hematocrit ( 27863252) Hip circumference ( 25673412) Hip circumference adjusted for BMI ( 28552196 25673412) Influenza A (H1N1) infection ( 26379185) Lymphocyte counts ( 27863252) Mild influenza (H1N1) infection ( 26379185) Multiple sclerosis ( 31604244 27386562) Offspring birth weight ( 31043758) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Weight ( 28552196)	Asthma ( 31619474) Carotid plaque burden ( 28282560) Insomnia symptoms (never/rarely vs. sometimes/usually) ( 30804566) Insomnia symptoms (never/rarely vs. usually) ( 30804566)
Interacting Genes		30 interacting genes: ASB6 BANP BYSL DNMT1 KDM1A LRRK2 LSM4 LZTR1 MAPK3 MAPK9 MORF4L1 MORF4L2 NGB OAZ3 PDE6G PHC2 PIK3R3 PLEKHF1 PLEKHF2 POLR2L PRKAA1 PRKAA2 SNRPB SOX2 SP100 SUMO1P1 THRA TSTD2 TTC19 ZCWPW1	9 interacting genes: AZIN2 BLZF1 C1orf94 GGN IKZF3 L3MBTL3 OAZ1 REL SMAD1
Entrez ID		84456	51686
HPRD ID		11222	18670
Ensembl ID		ENSG00000198945	ENSG00000143450
Uniprot IDs		Q96JM7	A0A0G2JH29 H0Y7Y4 Q9UMX2
PDB IDs		1WJQ 1WJS 3UT1 4FL6 4L59
Enriched GO Terms of Interacting Partners?
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