EIF1AD and STX11

Number of citations of the paper that reports this interaction (PubMedID 25416956)
381

Data Source:
BioGRID (two hybrid)

		EIF1AD	STX11
Description		eukaryotic translation initiation factor 1A domain containing	syntaxin 11
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus	Golgi Apparatus Plasma Membrane Synaptic Vesicle Endomembrane System Integral Component Of Membrane SNARE Complex Presynaptic Membrane Presynaptic Active Zone Membrane
	Molecular Function	Translation Initiation Factor Activity Protein Binding	SNARE Binding SNAP Receptor Activity Protein Binding
	Biological Process	Translational Initiation	Intracellular Protein Transport Exocytosis Vesicle Fusion Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Vesicle Docking Membrane Fusion
Pathways
Drugs
Diseases			Familial hemophagocytic lymphohistiocytosis (FHPL), including the following three diseases: Perforin deficiency; Munc deficiency; STX11 deficiency
GWAS		Acne (severe) ( 24927181) Bipolar disorder ( 31043756) Blood protein levels ( 30072576) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634)	Pre-treatment viral load in HIV-1 infection ( 31219150)
Interacting Genes		12 interacting genes: BEND7 CEP55 DPPA2 GLYR1 MEOX2 SDCBP SDCBP2 STAT1 STX11 TBC1D5 ZBTB14 ZBTB8A	64 interacting genes: APP AXIN1 BLOC1S6 BYSL C1orf109 CARD9 CCBE1 CCDC184 CCDC33 CCNK CDCA7L CRYBA4 CTBP2 CWF19L2 EIF1AD FAM110A FAM161A FAM74A4 FAM90A1 FARS2 GOLGA8EP GOLGA8F HAUS1 HGS IKBKG IKZF3 KAT5 KCTD9 KDM1A KLC3 KXD1 LENG1 LONRF1 MBIP MEOX2 MFAP1 MID2 NDC80 NTAQ1 PPP1R18 PRKAB2 PRPF31 PSMA3 PSMC3 RNF6 RUNX1T1 SH2D4A SLC38A2 SMARCE1 SNAP23 SNAP25 SNX3 SUV39H1 TAF6L TBK1 TCF4 TLE5 TNFRSF21 USHBP1 VAMP2 VPS52 ZCCHC10 ZNF417 ZNF587
Entrez ID		84285	8676
HPRD ID		14411	09231
Ensembl ID		ENSG00000175376	ENSG00000135604
Uniprot IDs		A0A024R5B9 Q8N9N8	O75558
PDB IDs		2DGY
Enriched GO Terms of Interacting Partners?
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