LTBP4 and CRY1

Number of citations of the paper that reports this interaction (PubMedID 21988832)
75

Data Source:
BioGRID (two hybrid)

		LTBP4	CRY1
Description		latent transforming growth factor beta binding protein 4	cryptochrome circadian regulator 1
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Extracellular Region Extracellular Space Extracellular Matrix Collagen-containing Extracellular Matrix	Nucleus Mitochondrion
	Molecular Function	Transforming Growth Factor Beta-activated Receptor Activity Integrin Binding Extracellular Matrix Structural Constituent Calcium Ion Binding Protein Binding Glycosaminoglycan Binding Transforming Growth Factor Beta Binding	Nucleotide Binding DNA Binding Double-stranded DNA Binding Deoxyribodipyrimidine Photo-lyase Activity DNA (6-4) Photolyase Activity Protein Binding Blue Light Photoreceptor Activity Protein Kinase Binding Phosphatase Binding Nuclear Hormone Receptor Binding Histone Deacetylase Binding E-box Binding
	Biological Process	Regulation Of Cell Growth Protein Folding Transforming Growth Factor Beta Receptor Signaling Pathway Multicellular Organism Development Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Regulation Of Proteolysis Growth Hormone Secretion Regulation Of Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Gluconeogenesis DNA Damage Induced Protein Phosphorylation Circadian Rhythm Response To Light Stimulus Blue Light Signaling Pathway Response To Activity Protein-chromophore Linkage Lipid Storage Negative Regulation Of Protein Ubiquitination Positive Regulation Of Protein Ubiquitination Response To Insulin Circadian Regulation Of Gene Expression Response To Glucagon Glucose Homeostasis Regulation Of Circadian Rhythm Negative Regulation Of Circadian Rhythm Entrainment Of Circadian Clock By Photoperiod Negative Regulation Of Gluconeogenesis Negative Regulation Of G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Transcription, DNA-templated Regulation Of DNA Damage Checkpoint Negative Regulation Of Glucocorticoid Receptor Signaling Pathway Negative Regulation Of Glucocorticoid Secretion
Pathways		Molecules associated with elastic fibres	Circadian Clock
Drugs
Diseases		Cutis laxa with severe pulmonary, gastrointestinal, and urinary abnormalities; Urban-Rifkin-Davis syndrome
GWAS		Lung function (FEV1/FVC) ( 26635082 30804560) Lung function (FVC) ( 30804560) Peak expiratory flow ( 30804560)	Morning person ( 30696823)
Interacting Genes		11 interacting genes: ATN1 ATXN7 CACNA1A CRKL CRY1 FBLN1 FRAT1 GFI1B ITSN2 RAC1 TGFB1	26 interacting genes: ARIH1 ARNTL BHLHE41 CBLB CLOCK CSNK1E DELEC1 FBXL3 GRN KRTAP4-12 LTBP4 MDFI NPAS2 NR1D2 PER1 PER2 PER3 PLSCR1 PPP2R1B PPP2R5D PPP2R5E SNRPD3 TIMELESS TRAF2 USP2 USP7
Entrez ID		8425	1407
HPRD ID		05274	09050
Ensembl ID		ENSG00000090006	ENSG00000008405
Uniprot IDs		A0A0C4DH07 B3KXY6 Q8N2S1	A2I2P0 Q16526
PDB IDs
Enriched GO Terms of Interacting Partners?
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