NCALD and PNP

Number of citations of the paper that reports this interaction (PubMedID 11964161)
19

Data Source:
HPRD (in vivo, in vitro)

		NCALD	PNP
Description		neurocalcin delta	purine nucleoside phosphorylase
Image		No pdb structure
GO Annotations	Cellular Component	Intracellular Cytosol Clathrin Coat Of Trans-Golgi Network Vesicle	Extracellular Region Nucleus Cytoplasm Cytosol Cytoskeleton Secretory Granule Lumen Extracellular Exosome Ficolin-1-rich Granule Lumen
	Molecular Function	Actin Binding Calcium Ion Binding Protein Binding Tubulin Binding Clathrin Binding Alpha-tubulin Binding	Nucleoside Binding Purine Nucleobase Binding Purine-nucleoside Phosphorylase Activity Drug Binding Phosphate Ion Binding Identical Protein Binding
	Biological Process	Regulation Of Systemic Arterial Blood Pressure Vesicle-mediated Transport Calcium-mediated Signaling	Nucleobase-containing Compound Metabolic Process Inosine Catabolic Process Purine Nucleotide Catabolic Process Nicotinamide Riboside Catabolic Process Immune Response Nucleotide Biosynthetic Process Urate Biosynthetic Process Positive Regulation Of T Cell Proliferation Response To Drug Purine-containing Compound Salvage Neutrophil Degranulation Positive Regulation Of Alpha-beta T Cell Differentiation Interleukin-2 Secretion
Pathways		Activation of Ca-permeable Kainate Receptor	Neutrophil degranulation Purine salvage Purine catabolism
Drugs			Cladribine Didanosine 8-azaguanine 2,6-Diamino-(S)-9-[2-(Phosphonomethoxy)Propyl]Purine Immucillin-G Guanine 2-Amino-7-[2-(2-Hydroxy-1-Hydroxymethyl-Ethylamino)-Ethyl]-1,7-Dihydro-Purin-6-One Peldesine 9-Deazainosine Guanosine Ribose-1-Phosphate 4'-Deaza-1'-Aza-2'-Deoxy-1'-(9-Methylene)-Immucillin-H, (3r,4r)-N-[9-Deazahypoxanthin-9-Yl)Methyl]-4-Hydroxymethyl-Pyrrolidin-3-Ol 3-Deoxyguanosine MT-Immucillin-H Hypoxanthine 9-(5,5-Difluoro-5-Phosphonopentyl)Guanine Inosine 9-DEAZAINOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE GUANOSINE-2',3'-O-ETHYLIDENEPHOSPHONATE GUANOSINE-2',3'-O-METHYLIDENEPHOSPHONATE
Diseases			Combined immunodeficiencies (CIDs), including the following nine diseases: X-linked hyper IgM syndrome; CD40 deficiency hyper IgM syndrome; Purine nucleoside phosphorylase (PNP) deficiency; Omenn syndrome; MHC deficiency (HLA-class I); MHC deficiency (HLA-class II); Zap-70 deficiency; p56 Lck deficiency; CD8 deficiency
GWAS		Age-related hearing impairment ( 24939585) Cerebral amyloid angiopathy ( 25188341) Coffee consumption ( 21876539) Cognitive performance ( 20125193) Gait speed in old age ( 28077804) LDL peak particle diameter (total fat intake interaction) ( 26112879) Medication use (beta blocking agents) ( 31015401) Microalbuminuria ( 26631737) Perceived sweetness of sucrose ( 31005972) Systolic blood pressure ( 30224653)	Angiotensin-converting enzyme inhibitor intolerance ( 28030426) Blood protein levels ( 30072576) Interferon alpha levels in systemic lupus erythematosus ( 25338677) Menopause (age at onset) ( 26414677)
Interacting Genes		9 interacting genes: ACTB C1QTNF2 CLTC DTX2 MEOX2 PNP TMEM14B TUBA4A TUBB	11 interacting genes: APLP1 CCDC90B LRIF1 NCALD NOS1AP RBM48 TFAM TFB2M TP53 UCHL5 ZHX1
Entrez ID		83988	4860
HPRD ID		09466	01247
Ensembl ID		ENSG00000104490	ENSG00000198805
Uniprot IDs		B2RB70 P61601	P00491 V9HWH6
PDB IDs			1M73 1PF7 1PWY 1RCT 1RFG 1RR6 1RSZ 1RT9 1ULA 1ULB 1V2H 1V3Q 1V41 1V45 1YRY 2A0W 2A0X 2A0Y 2OC4 2OC9 2ON6 2Q7O 3BGS 3D1V 3GB9 3GGS 3INY 3K8O 3K8Q 3PHB 4EAR 4EB8 4ECE 4GKA 5ETJ 5UGF
Enriched GO Terms of Interacting Partners?
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