KRTAP3-2 and GAD1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
108

Data Source:
BioGRID (two hybrid)

		KRTAP3-2	GAD1
Description		keratin associated protein 3-2	glutamate decarboxylase 1
Image		No pdb structure
GO Annotations	Cellular Component	Cytosol Keratin Filament	Plasma Membrane Cell Cortex Vesicle Membrane Axon Terminus Presynaptic Active Zone Inhibitory Synapse Clathrin-sculpted Gamma-aminobutyric Acid Transport Vesicle Membrane
	Molecular Function	Structural Molecule Activity Protein Binding	Glutamate Decarboxylase Activity Protein Binding Glutamate Binding Pyridoxal Phosphate Binding Protein-containing Complex Binding Protein N-terminus Binding
	Biological Process	Keratinization	Glutamate Catabolic Process Glutamate Decarboxylation To Succinate Chemical Synaptic Transmission Neurotransmitter Secretion Gamma-aminobutyric Acid Biosynthetic Process Protein-pyridoxal-5-phosphate Linkage Social Behavior Locomotory Exploration Behavior Response To Drug
Pathways		Keratinization	GABA synthesis GABA synthesis, release, reuptake and degradation MECP2 regulates transcription of genes involved in GABA signaling
Drugs			Pyridoxal Phosphate Pyridoxal Phosphate Pyridoxal Phosphate Glutamic Acid
Diseases			Cerebral palsy
GWAS			Menopause (age at onset) ( 26414677)
Interacting Genes		30 interacting genes: ARFGAP1 C5orf60 CNNM3 CREB5 DHRS1 GAD1 GATA1 HOXA1 HYAL2 KIF25-AS1 KRTAP10-1 KRTAP10-5 KRTAP12-2 KRTAP26-1 KRTAP4-12 KRTAP9-2 LCE1B LCE2A LCE3C LCE3E LCE4A MAPKBP1 NTM NUFIP2 OTX1 R3HDM2 TBC1D16 TRIM42 TRIP13 YIPF3	15 interacting genes: AGTRAP CMTM5 GAD2 HAAO KRT31 KRT40 KRTAP3-2 MAL2 PPP2CA PPP2CB PRKACA PRKCE STK3 TRIM23 TRIP6
Entrez ID		83897	2571
HPRD ID		13938	12011
Ensembl ID		ENSG00000212900	ENSG00000128683
Uniprot IDs		Q9BYR7	A0A0S2Z3V5 Q8IVA8 Q99259
PDB IDs			2OKJ 3VP6
Enriched GO Terms of Interacting Partners?
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